Picore q2t

Manufactured by Siemens

PICORE Q2T is a high-performance laboratory equipment designed for various analytical applications. It features a compact and modular design, allowing for versatile configuration to meet specific laboratory requirements. The core function of PICORE Q2T is to provide precise and reliable measurements, supporting researchers and scientists in their analytical workflows.

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Lab products found in correlation

3t scanner, by Siemens (1 mentions)

2 protocols using picore q2t

Neonatal Hypoxic-Ischemic Encephalopathy Imaging

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Seventy-three full term neonates were identified as a sample of convenience for a retrospective case-control study following an IRB-approved protocol, between January 2008 and July 2018. A waiver of consent/parental permission, assent and HIPAA authorization has been approved by our IRB. All neonates had T1WI, T2WI, DWI images and PASL of the brain. For clarity, T1WI, T2WI, and DWI sequences will be referred as conventional MRI.
The neonates were divided into three groups: control, HIE/MRI⊖, HIE/MRI⊕. The patients in HIE/MRI⊖ group were with clinical HIE and normal conventional MRI, while the patients from HIE/MRI⊕ group were with clinical HIE and abnormal conventional MRI. There was a fourth additional group combining all HIE patients from the HIE/MRI⊖ and HIE/MRI⊕ groups, called HIE/MRI± group.
The PASL images were acquired with perfusion model of PICORE Q2T from a Siemens 3T scanner using the following parameters: bolus time Tl₁ = 700 ms, inversion time T₁ = 1,800 ms, TR/TE = 2,600/14 ms, 14 slices, FOV = 200 × 200 mm, 64 × 64 matrix, voxel size=2.8 × 2.8 × 6.0 mm³, flip angle = 90⁰, 45 label/control image pairs. The reason for not using pseudo continuous arterial spin label (PCASL) is that only PASL is clinically available in our retrospective study.

Zheng Q., Martin-Saavedra J.S., Saade-Lemus S., Vossough A., Zuccoli G., Gonçalves F.G., Freeman C.W., Ouyang M., Singh V., Padula M.A., Demauro S.B., Flibotte J., Eichenwald E.C., Detre J.A., Sze R.W., Huang H, & Hwang M. (2020). Cerebral Pulsed Arterial Spin Labeling Perfusion Weighted Imaging Predicts Language and Motor Outcomes in Neonatal Hypoxic-Ischemic Encephalopathy. Frontiers in Pediatrics, 8, 576489.

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Neonatal Brain Perfusion Imaging Protocol

Cited 2 times

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The PASL images were acquired with perfusion model of PICORE Q2T from a 32-channel coil 3T Siemens scanner using the following parameters: bolus time TI₁=700ms, inversion time TI =1800ms, TR/TE=2600/14ms, 14 slices, FOV=200×200mm, 64×64 matrix, voxel size=3.1×3.1×6.0mm³, flip angle=90°, 45 label/control image pairs. The cerebral blood flow (CBF) map was computed from the pulsed PASL images with a single-compartment model[18 (link)] with image preprocessing by ASL data processing toolbox (ASLtbx)[19 (link)]. The parameters utilized in calculating the CBF map were: The blood-brain partition coefficient λ = 1.10 mL/g for neonates[20 (link)], T_1b = 1825ms and T_2b = 191ms for neonates[21 (link)], labeling efficiency α = 0.98 for PASL[18 (link)]. The relaxed equilibrium magnetization M_0b was calculated on cerebrospinal fluid (CSF), white matter (WM), and gray matter (GM) separately from the proton density-weighted image, with the signal ratios of the tissue type being R_CSF = 0.87, R_WM = 1.19, R_GM = 0.98 [22 ] and T_2CSF = 250ms, T_2WM = 222 ms, T_2GM = 143 m [23 (link)] used for neonates.

Zheng Q., Viaene A.N., Freeman C.W, & Hwang M. (2020). Radiologic-pathologic evidence of brain injury: Hypoperfusion in the Papez circuit results in poor neurodevelopmental outcomes in neonatal hypoxic ischemic encephalopathy. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 37(1), 63-68.

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