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Picore q2t

Manufactured by Siemens

PICORE Q2T is a high-performance laboratory equipment designed for various analytical applications. It features a compact and modular design, allowing for versatile configuration to meet specific laboratory requirements. The core function of PICORE Q2T is to provide precise and reliable measurements, supporting researchers and scientists in their analytical workflows.

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Lab products found in correlation

2 protocols using picore q2t

1

Neonatal Hypoxic-Ischemic Encephalopathy Imaging

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Seventy-three full term neonates were identified as a sample of convenience for a retrospective case-control study following an IRB-approved protocol, between January 2008 and July 2018. A waiver of consent/parental permission, assent and HIPAA authorization has been approved by our IRB. All neonates had T1WI, T2WI, DWI images and PASL of the brain. For clarity, T1WI, T2WI, and DWI sequences will be referred as conventional MRI.
The neonates were divided into three groups: control, HIE/MRI⊖, HIE/MRI⊕. The patients in HIE/MRI⊖ group were with clinical HIE and normal conventional MRI, while the patients from HIE/MRI⊕ group were with clinical HIE and abnormal conventional MRI. There was a fourth additional group combining all HIE patients from the HIE/MRI⊖ and HIE/MRI⊕ groups, called HIE/MRI± group.
The PASL images were acquired with perfusion model of PICORE Q2T from a Siemens 3T scanner using the following parameters: bolus time Tl1 = 700 ms, inversion time T1 = 1,800 ms, TR/TE = 2,600/14 ms, 14 slices, FOV = 200 × 200 mm, 64 × 64 matrix, voxel size=2.8 × 2.8 × 6.0 mm3, flip angle = 900, 45 label/control image pairs. The reason for not using pseudo continuous arterial spin label (PCASL) is that only PASL is clinically available in our retrospective study.
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2

Neonatal Brain Perfusion Imaging Protocol

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The PASL images were acquired with perfusion model of PICORE Q2T from a 32-channel coil 3T Siemens scanner using the following parameters: bolus time TI1=700ms, inversion time TI =1800ms, TR/TE=2600/14ms, 14 slices, FOV=200×200mm, 64×64 matrix, voxel size=3.1×3.1×6.0mm3, flip angle=90°, 45 label/control image pairs. The cerebral blood flow (CBF) map was computed from the pulsed PASL images with a single-compartment model[18 (link)] with image preprocessing by ASL data processing toolbox (ASLtbx)[19 (link)]. The parameters utilized in calculating the CBF map were: The blood-brain partition coefficient λ = 1.10 mL/g for neonates[20 (link)], T1b = 1825ms and T2b = 191ms for neonates[21 (link)], labeling efficiency α = 0.98 for PASL[18 (link)]. The relaxed equilibrium magnetization M0b was calculated on cerebrospinal fluid (CSF), white matter (WM), and gray matter (GM) separately from the proton density-weighted image, with the signal ratios of the tissue type being RCSF = 0.87, RWM = 1.19, RGM = 0.98 [22 ] and T2CSF = 250ms, T2WM = 222 ms, T2GM = 143 m [23 (link)] used for neonates.
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