Animal protocol AC-AABP4566 was compliant with ARRIVE guidelines and approved for this research by the Columbia University Institutional Animal Care and Use Committee (IACUC). B6 (Cg)-Tyrc-2J/J mice (B6-albino), 6–9 weeks old, were acquired from Jackson Laboratories (Bar Harbor, ME) for this study (n = 51).
B6 cg tyrc 2j j b6 albino mice
Manufactured by Jackson ImmunoResearch
Sourced in Montenegro
B6(Cg)-TyrC-2J/J (B6 albino) mice are a strain of laboratory mice that have a naturally-occurring tyrosinase gene mutation, resulting in albinism. These mice are commonly used as a model system in various research applications due to their unique genetic characteristics.
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Lab products found in correlation
B6 pl thy1a cyj b6 thy1.1, by Jackson ImmunoResearch (2 mentions)
Ova specific ot 2 tcr transgenic c57bl 6 mice, by Jackson ImmunoResearch (2 mentions)
Cxcr3tm1dgen j b6 cxcr3 ko, by Jackson ImmunoResearch (2 mentions)
C57bl 6, by Jackson ImmunoResearch (1 mentions)
Fvb nj, by Jackson ImmunoResearch (1 mentions)
8 protocols using b6 cg tyrc 2j j b6 albino mice
1
Albino Mice Study on B6 Strain
2
Albino B6 Mice for Experiments
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Animal protocol AC-AAAW1464 was reviewed and approved for this study by the internal animal ethics committee, the Columbia University Institutional Animal Care and Use Committee (IACUC), and was in compliance with the ARRIVE guidelines. Six to nine-week-old male B6 (Cg)-Tyrc-2J/J mice (B6-albino) purchased from Jackson Laboratories (Bar Harbor, ME) were used in these experiments (n = 41).
3
Modeling CALM-AF10 Leukemia in B6 Albino Mice
4
Mice Housing and Handling Protocol
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C57BL/6 and B6(Cg)-Tyrc-2J/J (B6 albino) mice were obtained from Jackson Laboratory (Bar Harbor, ME, USA) and housed with Resource Animal Resources at the University of Minnesota with 12 hour light/dark cycle and food ad libitum. All animal studies followed the guidelines of the National Institutes of Health and the Association for Research in Vision and Ophthalmology, and all experiments were approved by the Institutional Animal Care and Use Committee at the University of Minnesota.
5
Albino Mice AAV Transduction Protocol
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All procedures were approved by the Institutional Animal Care and Use Committee of Mispro Biotech Services (protocol 2021-ASK-03) and are in accordance with the guidelines established by the National Institutes of Health for the humane treatment of animals. Male B6(Cg)-Tyrc-2J/J (B6 Albino) mice (8–10 weeks) were obtained from the Jackson Laboratory (Bar Harbor, ME) and were housed in a temperature-controlled, 12-h light-cycled facility. Mice were given free access to 5053 irradiated rodent feed (LabDiet, St. Louis, MO) and reverse osmosis-filtered water via an automatic system throughout each study. Male mice were utilized for this study as the estrus cycle in female mice negatively affects AAV transduction28 .
6
Metastatic Colonization Assays in Mice
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All animal experiments were conducted in accordance with a protocol approved by the Memorial Sloan Kettering Cancer Center (MSKCC) Institutional Animal Care and Use Committee (IACUC). Athymic nude (Hsd:Athymic Nude-Foxn1nu, ENVIGO, order code: 069) female mice aged between 5–7 weeks were used for metastatic colonization assays of MDA231-BrM cells and HCC1954-BrM cells. B6(Cg)-Tyrc-2J/J (B6 albino mice, strain #: 000058) and FVB/NJ (strain #: 001800) female mice aged between 5–7 weeks, both from The Jackson Laboratory, were used for metastatic colonization assays of E0771-BrM cells and MMTV-ErbB2-BrM cells, respectively.
7
Transgenics for Immune Cell Tracking
8
Transgenics for Immune Cell Tracking
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All animal procedures were approved by the Institutional Animal Care and Use Committee of the University of Rochester. Female and male mice were bred and maintained in pathogen-free conditions in group housing, used between 6-14 weeks of age, and euthanized in accordance with the University of Rochester guidelines. B6(Cg)-Tyrc-2J/J (Albino B6) mice, OVA-specific OT-II TCR transgenic C57BL/6 mice, B6.PL-Thy1a/CyJ (B6 Thy1.1) and Cxcr3tm1Dgen/J (B6 CXCR3 KO) mice were purchased from The Jackson Laboratory. REX3 (Reports the Expression of CXCR3 ligands) B6 mice were provided by A. Luster, Massachusetts General Hospital. WT C57BL/6 mice were purchased from the National Cancer Institute, Bethesda, MD. REX3 mice were crossed to Albino B6 mice. OT-II TCR transgenic mice were crossed to CXCR3 KO mice. Kaede transgenic mice were obtained from RIKEN.
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