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Myricetin

Manufactured by Selleck Chemicals
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Sourced in China, United States

Myricetin is a flavonoid compound that can be used as a lab equipment product. It functions as an antioxidant and has the chemical formula C₁₅H₁₀O₇.

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Lab products found in correlation

Luteolin, by Selleck Chemicals (2 mentions) Baicalein, by Selleck Chemicals (2 mentions) Fisetin, by Selleck Chemicals (1 mentions) Pirfenidone, by Selleck Chemicals (1 mentions) Resveratrol, by Selleck Chemicals (1 mentions) Epigallocatechin gallate (egcg), by Selleck Chemicals (1 mentions) Apigenin, by Merck Group (1 mentions) Curcumin, by Selleck Chemicals (1 mentions) Rutin, by Selleck Chemicals (1 mentions) Quercetin, by Merck Group (1 mentions) Catechin, by Merck Group (1 mentions) Bapta am, by Selleck Chemicals (1 mentions) Chloroquine cq, by Merck Group (1 mentions) Tunicamycin, by Merck Group (1 mentions) Apigenin, by Selleck Chemicals (1 mentions) Gossypol acetate, by Selleck Chemicals (1 mentions) Quercetin dihydrate, by Selleck Chemicals (1 mentions) Caffeic acid, by Selleck Chemicals (1 mentions) Indirubin, by Selleck Chemicals (1 mentions) Kaempferol, by Selleck Chemicals (1 mentions)

6 protocols using myricetin

1

Flavonoid Compounds Protocol

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Chemicals were from Sigma-Aldrich (St. Louis) unless otherwise noted. The flavonoids were purchased from Selleckchem (Houston, TX): resveratrol (Cat #S1396), fisetin (Cat #S2298), luteolin (Cat #S2320), rutin (Cat #S2350), epigallocatechin gallate (EGCG, Cat #S2250), curcumin (Cat #S1848), pirfenidone (Cat #S2907), and myricetin (Cat #S2326). Apigenin, catechin, and quercetin were purchased from Sigma-Aldrich (Cat #1760595, #1096790 and 1,592,409, respectively).
Yousefzadeh M.J., Zhu Y., McGowan S.J., Angelini L., Fuhrmann-Stroissnigg H., Xu M., Ling Y.Y., Melos K.I., Pirtskhalava T., Inman C.L., McGuckian C., Wade E.A., Kato J.I., Grassi D., Wentworth M., Burd C.E., Arriaga E.A., Ladiges W.L., Tchkonia T., Kirkland J.L., Robbins P.D, & Niedernhofer L.J. (2018). Fisetin is a senotherapeutic that extends health and lifespan. EBioMedicine, 36, 18-28.
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2

Dissolving Compounds for Cell Studies

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Myricetin (Selleck Chemicals, Shanghai, China), BAPTA-AM (Selleck Chemicals, Shanghai, China), and tunicamycin (Sigma Aldrich, St. Louis, USA) were dissolved in 100% dimethyl sulfoxide (DMSO). Chloroquine (CQ, Sigma Aldrich, St. Louis, USA) was dissolved in PBS. Chemicals were further diluted with cell culture medium for in vitro studies or PBS for in vivo studies to the indicated concentration.
Ji A., Hu L., Ma D., Qiang G., Yan D., Zhang G, & Jiang C. (2022). Myricetin Induces Apoptosis and Protective Autophagy through Endoplasmic Reticulum Stress in Hepatocellular Carcinoma. Evidence-based Complementary and Alternative Medicine : eCAM, 2022, 3115312.
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3

Dietary Compounds from Selleckchem in Research

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The following dietary compounds were purchased from Selleckchem: apigenin (Selleckchem, Cat#- S2262), baicalein (Selleckchem, Cat#- S2269), baicalin (Selleckchem, Cat#- S2268), berberine hydrochloride (Selleckchem, Cat#- S2271), Cat#- S2268), caffeic acid (Selleckchem, Cat#- S2277), dihydromyricetin (Selleckchem, Cat#- S2399), emodin (Selleckchem, Cat#- S2295), (−)-epigallacatechin gallate (Selleckchem, Cat#- 2250), gossypol acetate (Selleckchem, Cat#- S2303), hematoxylin (Selleckchem, Cat#- S2384), indirubin (Selleckchem, Cat#- S2386), kaempferol (Selleckchem, Cat#- S2314), luteolin (Selleckchem, Cat#- S2320), morin hydrate (Selleckchem, Cat#- S2325), myricetin (Selleckchem, Cat#- S2326), myricitrin (Selleckchem, Cat#- S2327), palmatine chloride (Selleckchem, Cat#- S2397) and quercetin dihydrate (Selleckchem, Cat#- S2347).
Evans L., Shen Y., Bender A., Burnett L.E., Li M., Habibian J.S., Zhou T, & Ferguson B.S. (2021). Divergent and Overlapping Roles for Selected Phytochemicals in the Regulation of Pathological Cardiac Hypertrophy. Molecules, 26(5), 1210.
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4

Metabolic Modulation Compounds Protocol

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CB-839, Quercetin, Myricetin (Selleckchem); Glutathione ethyl ester, Buthionine sulfoximine, Curcumin, Bafilomycin A1 (Sigma); Tigecycline, Rotenone, Oligomycin (Cayman); UK5099 (Tocris); Sulfasalazine (Fluka); Auranofin (Adipogen); l-aspartic acid 4-methyl ester hydrochloride (Alfa Aesar) were used.
Kshattry S., Saha A., Gries P., Tiziani S., Stone E., Georgiou G, & DiGiovanni J. (2019). Enzyme-mediated depletion of l-cyst(e)ine synergizes with thioredoxin reductase inhibition for suppression of pancreatic tumor growth. NPJ Precision Oncology, 3, 16.
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5

Sourcing and Storage of Inhibitory Compounds

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Chemical inhibitors were obtained from commercial sources: SSYA10-001 (Glixx Lab #GLXC-20411), Cangrelor (Sigma-Aldrich, #SML2004), Cepharanthine (Selleck, #S4238), Lumacaftor (Selleck, #S1565), Ribavirin (Sigma-Aldrich, #R9644), Baicalein (Selleck, #2268), Myricetin (Selleck, #S2326), Punicalagin (Selleck, #S9131) Scutarellein (Selleck, #S9120), and Tideglusib (Selleck, #S2823). Inhibitors were suspended in the appropriate solvent and stored as per manufacturer's recommendations.
Inniss N.L., Rzhetskaya M., Ling-Hu T., Lorenzo-Redondo R., Bachta K.E., Satchell K.J.F, & Hultquist J.F. (2024). Activity and inhibition of the SARS-CoV-2 Omicron nsp13 R392C variant using RNA duplex unwinding assays. SLAS discovery : advancing life sciences R & D, 29(3).
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6

Myricetin Modulates Inflammatory Pathways

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Myricetin was purchased from Selleck Chemicals Co. Ltd. (Houston, TX, USA). Sodium carboxymethyl cellulose (CMC-Na) was obtained from Makclin Biochemical Co., Ltd. (Shanghai, China). Dimethyl sulfoxide (DMSO) and lipopolysaccharide (LPS) were purchased from Sigma Chemical, Co. Ltd. (St. Louis, MO, USA). Myricetin was prepared as stocks in CMC-Na and diluted to various concentrations in medium.
The antibodies were obtained as following: rabbit anti-IL-12A, rabbit anti-IRF5, rabbit anti-CD163, rabbit anti-Ym-1/Ym-2, rat anti-TREM1, rabbit anti-NF-κB, rabbit anti-phosphor-NF-κB (Abcam, Cambridge, MA); rabbit anti-α-SMA, rabbit anti-F4/80, rabbit anti-Iκ-Bα, rabbit anti-phospho-Iκ-Bα, rabbit anti-JNK, rabbit anti-phospho-JNK, mouse anti-STAT3, rabbit anti-phospho-STAT3 (CST, Danvers, Massachusetts, USA); HRP-linked goat anti-rabbit IgG (Jackson Labs Technologies, Inc., Las Vegas, NV); rabbit anti-GAPDH and rabbit anti-β-actin (HuaAn Technologies, Inc., Hangzhou, China). HRP-linked goat anti-rat IgG (Byotime Institute Biotechnology, Shanghai, China), Cy3 conjugated goat anti-rabbit IgG H&L (Servicebio, Wuhan, China), Alexa Fluor 488 goat anti-rat IgG H&L (Invitrogen, USA).
Yao Q., Li S., Li X., Wang F, & Tu C. (2020). Myricetin Modulates Macrophage Polarization and Mitigates Liver Inflammation and Fibrosis in a Murine Model of Nonalcoholic Steatohepatitis. Frontiers in Medicine, 7, 71.
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