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G8201

Manufactured by Promega
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Sourced in United States

The G8201 is a laboratory equipment product from Promega. It is designed to perform a core function within the laboratory setting, but a detailed description while maintaining an unbiased and factual approach is not available.

Automatically generated - may contain errors

Lab products found in correlation

G8091, by Promega (2 mentions) G8211, by Promega (2 mentions) Docetaxel, by Selleck Chemicals (1 mentions)

2 protocols using g8201

1

Caspase Activation in OVCAR3 Cells

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Caspase 3/7, Caspase 8, and Caspase 9 activity was measured in OVCAR3 cells lines using Caspase-Glo luminescence assays (G8091, G8201, G8211, Promega, Madison, WI, USA) in accordance with the manufacturer’s specifications after exposing cells to docetaxel 4 nM (#S1148, Selleckchem, Houston, TX, USA) alone and in combination with birinapant 400 nM for 24 h. All drug exposures occurred with 10 ng/mL of TNF-α and without TNF-α. Activity data were normalized to viable cell number, measured in an identical plate by the XTT assay as described.
Noonan A.M., Cousins A., Anderson D., Zeligs K.P., Bunch K., Hernandez L., Shibuya Y., Goldlust I.S., Guha R., Ferrer M., Thomas C.J, & Annunziata C.M. (2020). Matrix Drug Screen Identifies Synergistic Drug Combinations to Augment SMAC Mimetic Activity in Ovarian Cancer. Cancers, 12(12), 3784.
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2

Caspase Activation in Ovarian Cancer

Check if the same lab product or an alternative is used in the 5 most similar protocols
Caspase 3/7, Caspase 8, and Caspase 9 activity were measured in OVCAR3 and OVCAR8 cells lines using Caspase-Glo luminescence assays (Promega, G8091, G8201, G8211) according to the manufacturer’s specifications after exposing cells to panobinostat 10 nM alone and in combination with birinapant 20 μM for 24 h. All drug exposures occurred with or without 10 ng/mL of TNF-α. Activity data were normalized to viable cell number and measured in an identical plate by XTT assay as described.
Shibuya Y., Kudo K., Zeligs K.P., Anderson D., Hernandez L., Ning F., Cole C.B., Fergusson M., Kedei N., Lyons J., Taylor J., Korrapati S, & Annunziata C.M. (2023). SMAC Mimetics Synergistically Cooperate with HDAC Inhibitors Enhancing TNF-α Autocrine Signaling. Cancers, 15(4), 1315.
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