The drug content of tablets (n = 6) was determined in a 0.1 N HCl solution after being stirred in 50 mL volumetric flasks for 24 h containing to ensure complete dissolution. Samples were diluted and analyzed spectrophotometrically at 240 nm (U-1900 UV−VIS Spectrophotometer, Hitachi, Tokyo, Japan).
U 1900 uv vis spectrophotometer
Manufactured by Hitachi
Sourced in Japan
The U-1900 UV−VIS Spectrophotometer is a compact and versatile instrument designed for accurate analysis of sample absorbance within the ultraviolet and visible light spectrum. It features a high-resolution display, simple user interface, and robust construction for reliable performance in a variety of laboratory settings.
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Lab products found in correlation
2 protocols using u 1900 uv vis spectrophotometer
1
Spectrophotometric Tablet Drug Content
2
In Vitro Drug Release from Tablets
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The in vitro drug release from tablets (n = 6) was determined using a type II dissolution apparatus (AT7, Sotax, Aesch, Switzerland) with a paddle speed of 100 rpm. The experiments were performed in 900 mL 0.1 N HCl solution at 37.0 ± 0.5 °C. Samples were withdrawn at pre-set times (between 0 and 180 min), filtered through a 0.22 μm MCE filter (Merck, Burlington, MA, USA) and analyzed spectrophotometrically at 240 nm (U-1900 UV−VIS Spectrophotometer, Hitachi, Tokyo, Japan). Fresh dissolution medium was added after each sample was collected to keep the volume inside the vessel constant.
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