Gemini gxl 16 pet scanner

PET/CT scanning was performed using a GEMINI GXL-16 PET scanner (PHILIPS). All patients received intravenous injections of [¹³N]N-NH3 (dose range: 444–592 MBq). One day after the injection, [¹¹C]C-MET (dose range: 280–450 MBq) was also injected intravenously. A 15-min emission image for [¹³N]N-NH3 or [¹¹C]C-MET was obtained, beginning 5 min after the [¹³N]N-NH3 injection or 10 min after the [¹¹C]C-MET injection. [¹³N]N-NH3 or [¹¹C]C-MET was synthesized according to the methods described in the literature. Increased tracer uptake was in accordance with the criteria, namely that the region had a significantly higher tracer uptake than the surroundings. The pattern of tracer uptake and the maximum standard uptake value (SUVmax) were recorded and analyzed by two nuclear medicine experts.

As Qiao He reported (29 (link)), no specific preparation of the patients was required before 68Ga-DOTANOC PET-CT and 18F-FDG examination. PET-CT imaging was performed with a Gemini GXL 16 PET scanner (Philips Healthcare). One hundred eleven to 185 MBq (3–5 mCi) 68Ga-DOTANOC or a dose of 5.18 MBq (0.14 mCi)/kg FDG was injected intravenously, and serial scanning was performed. Serial scanning from head to mid-thigh was performed approximately 45–60 min after the injection. Following low radiation dose CT acquisition with a slice thickness of 5 mm, PET acquisition was performed for 1.5 min per bed position for 7–8 beds using a slice thickness of 4 mm. CT-based attenuation correction of the emission data was employed. PET images were reconstructed by the Line of Response RAMLA algorithm.
18F-FDG and 68Ga-DOTANOC PET-CT studies were performed at least 24 h apart.