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Multilevel ct

Manufactured by Bayer
Sourced in United States

The Multilevel CT is a laboratory equipment designed for computed tomography (CT) imaging. It provides high-resolution, multi-dimensional scans of samples or specimens. The core function of the Multilevel CT is to capture detailed, three-dimensional images through a series of X-ray projections, enabling researchers to analyze the internal structure and composition of their samples.

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7 protocols using multilevel ct

1

4-Phase Liver CT Evaluation Protocol

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The 4P liver CT evaluation consisted of pre-contrast, arterial, portal and delayed phase. Patients were randomly allocated to one of the CT scanners with multi-detector (≥ 4) at our institution (MX 8000, Philips Healthcare, Bothell, WA, USA; Lightspeed Ultra, GE Healthcare, Waukesha, WI, USA; Sensation 16, Siemens Healthcare, Elrangen, Germany). The acquisition protocol was uniform regardless of the type of CT scanners. After scanning the pre-contrast phase, contrast media (1.5 mL/kg of Ultravist 370, Bayer-Schering Pharmaceuticals, Berlin, Germany) was injected at a rate of 2–4 mL/sec using a power injector (Multilevel CT, Medrad, Indianola, PA, USA) followed by saline flush. The arterial phase was obtained using the bolus tracking method, and the portal and delayed phases were obtained 70 and 180 seconds after contrast media injection, respectively. All scans were performed using standard kVp and automatic tube-current modulation for each vendor, when available.
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2

MSCT Imaging of Pelvic Anatomy

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MSCT scanning was performed by using a LightSpeed VCT (GE Healthcare, Milwaukee, WI, USA) through the whole pelvis. The images were acquired with a contiguous section thickness of 1.25 mm, a field of view of 400 × 400 mm, a peak voltage of 120 kVp, a tube current of 200 mA, and a matrix of 512 × 512. For contrast-enhanced imaging, a bolus intravenous dose of 80 ml of nonionic iodinated contrast agent (Ultravist 300; Schering, Berlin, Germany) was administered using a power injector (Multilevel CT; Medrad, Pittsburgh, PA, USA), through an 18-gauge intravenous catheter placed in the antecubital vein at a rate of 2.5 ml/s. After the contrast material injection, 20 ml of normal saline was administered immediately. The scanning was initiated 60 s after the onset of contrast injection. The axial images were reconstructed in both sagittal and coronal planes with a section thickness of 3 mm.
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3

Multidetector CT Scanning for Splenic Lesions

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Various types of multidetector computed tomography scanners with 8–320 channels were used to screen patients in the two hospital databases. Commonly used multidetector CT scanners include: an 8-channel scanner (LightSpeed Ultra, GE Healthcare, Milwaukee, WI, USA, [n = 7]), a 16-channel scanner (Sensation 16, Siemens, Forchheim, Germany, [n = 18]; LightSpeed Pro 16, GE Healthcare, [n = 13]; Mx8000, Philips Medical Systems, Best, the Netherlands, [n = 7]), 64-channel and 320-channel scanners (Brilliance 64, Philips Medical Systems, [n = 22]; LightSpeed VCT, GE Healthcare, [n = 14]; Aquilion, Toshiba Medical Systems, Otawara, Japan, [n = 7]). Table 1 summarizes the CT parameters of popular CT scanners. All of the CT images included portal venous phase, which was used to evaluate splenic lesions. The portal venous scans were acquired at fixed delays (70–80 seconds) after the administration of 1.5–2.0 mL per kilogram of body weight of nonionic contrast material at a rate of 2.0–3.5 mL/sec with a pump (Multilevel CT; Medrad, Indianola, PA, USA) via an 18-gauge catheter placed in a peripheral vein.
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4

Multi-Detector CT Imaging Protocol

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CT examinations were performed using the following CT scanners: Discovery CT750 HD (64-channel scanner, GE Healthcare, Milwaukee, WI, USA, n = 4), Brilliance 64 (64-channel scanner, Philips Healthcare, Cleveland, OH, USA, n = 10), Sensation 16 (16-channel scanner, Siemens Medical Solutions, Erlangen, Germany, n = 5), and LightSpeed Ultra (8-channel scanner, GE Healthcare, Milwaukee, WI, USA, n = 1). For 8-, 16-, and 64-detector CT examinations, detector collimations of 1.25, 0.75, and 0.625 mm, respectively, were used. A section thickness of 3.0–3.2 mm with a 2.5 to 3-mm reconstruction interval, a field of view of 300–370 mm, a gantry rotation time of 0.5 s, an effective amperage setting of 150–200 mAs, and a peak voltage of 120 kVp were used for all of the CT scanners. All patients underwent dual-phase CT during the arterial and portal venous phases. For dynamic phase imaging, a fixed dose of 1.5 ml of nonionic contrast material (iopromide [370 mg of iodine permilimeter], Ultravist 370; Schering, Berlin, Germany) per kilogram of body weight (555 mgI/kg) was injected at a rate of 2.0–4.0 mL/sec using a power injector (Multilevel CT; Medrad, Indianola, PA, USA).
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5

Standardized CT Protocol for Dynamic Abdominal Imaging

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CT examinations were performed using the following two CT scanners: Sensation 16 (n = 74), and Brilliance 64 (n = 28). For 16- and 64-detector CT examinations, detector collimations of 0.75 and 0.625 mm, respectively, were used. A section thickness of 2.5–5.0 mm with a 2- to 3- mm reconstruction interval, a field of view of 300–370 mm, a gantry rotation time of 0.5 s, an effective amperage setting of 150–200 mAs, and a peak voltage of 120 kVp were used for all of the CT scanners. All of the patients’ CT protocols included venous phase images. For dynamic phase imaging, a fixed dose of 1.5–2.0 mL of nonionic contrast material (iopromide [370 mg of iodine per millimeter], Ultravist 370; Bayer HealthCare) per kilogram of body weight (555 mgI/kg) was injected at a rate of 2.0–4.0 mL/sec using a power injector (Multilevel CT; Medrad). The venous phase scans were obtained 70–80 seconds after administration of the IV contrast material.
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6

MDCT Imaging of Abdominal Aorta Contrast Enhancement

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In this study, 21,745 individuals underwent MDCT consisting of precontrast, arterial, and portal phases. CT scans were obtained using one of the following commercially available MDCT scanners: LightSpeed Ultra 8-channel CT scanner (GE Healthcare, Milwaukee, WI) and Somatom definition dual-source CT scanner (Siemens Medical Solutions, Malvern, PA). The images with 3-mm thick sections were acquired. Using a power injector (Multilevel CT; Medrad, Pittsburgh, PA), 120 mL of nonionic contrast material (Iopromide, Ultravist 370; Schering, Berlin, Germany) was administered at a rate of 3 mL/s through an 18-gauge, plastic, intravenous catheter placed in an antecubital vein, followed by a 20 mL flush of sterile saline. For arterial phase imaging, the scanning delay was determined using an automatic bolus tracking technique provided by the CT manufacturer. Contrast enhancement was automatically calculated by placing the region-of-interest cursor over the vessel of interest, that is, the abdominal aorta, and the level of the trigger threshold was set at an increase of 100 Hounsfield units.
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7

Thyroid MSCT Imaging Protocol

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The thyroid function of all patients was checked before MSCT scan, which was never hyperthyroid. MSCT examinations were performed with a Light Speed VCT 64 Slice CT scanner (GE Healthcare, Milwaukee, WI, USA) through the neck. The images were acquired with 1.25 mm contiguous section thickness, a field of view of 260×260 mm, a peak voltage of 120 kVp, a tube current of 200 mA and a matrix of 512×512. For contrast-enhanced imaging, a bolus intravenous dose of 80-90 mL of nonionic iodinated contrast agent (Ultravist 300; Schering, Berlin, Germany) was administered using a power injector (Multilevel CT; Medrad, Pittsburgh, PA, USA), through an 18-gauge intravenous catheter placed in the antecubital vein at a rate of 2.5 ml/s. After the contrast material injection, 20 ml of normal saline was administered immediately. The scan was initiated 40-45 seconds after the onset of contrast injection. The axial images were reconstructed in both sagittal and coronal planes with a section thickness of 3 mm.
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