Alkaloid natural product library was obtained from TargetMol (TargetMol, Shanghai, China, L6110). RSL3 (Selleckchem, Houston, TX, S8155) and erastin (Selleckchem, S7242) were used to induce ferroptosis. Staurosporine (Selleckchem, S1421), rapamycin (Selleckchem, S1039), rotenone (Selleckchem, S2348)/H2O2 (Sigma-Aldrich, MO, 31642) were used to induce apoptosis, autophagy, and necrosis, respectively. Ferrostatin-1 (Selleckchem, S7243)/liproxstatin-1 (Selleckchem, S7699), Z-VAD-FMK (Selleckchem, S8102), 3-methyladenine (Selleckchem, S2767), necrostatin-1 (Selleckchem, S8037) were used to inhibit ferroptosis, apoptosis, autophagic cell death and necrosis, respectively. N-acetylcysteine (NAC) (Selleckchem, S1623) is an antioxidant that removes ROS. BBIQ compounds used in the study were all obtained from Selleckchem which include fangchinoline (S3611), cepharanthine (S4238), berbamine (S9141), dauricine (S9295), daurisoline (S9150), neferine (S5144), isoliensinine (S9247), liensinine (S9411).
Daurisoline
Manufactured by Selleck Chemicals
Sourced in United States
Daurisoline is a laboratory chemical reagent used in the analysis and purification of organic compounds. It is a colorless, crystalline solid with a melting point of approximately 182-184°C. Daurisoline is commonly utilized in various chemical procedures and analytical techniques, but its specific applications and intended uses are not provided within the scope of this factual description.
Automatically generated - may contain errors
Lab products found in correlation
Necrostatin 1, by Selleck Chemicals (1 mentions)
N acetylcysteine nac, by Selleck Chemicals (1 mentions)
3 methyladenine, by Selleck Chemicals (1 mentions)
Cepharanthine, by Selleck Chemicals (1 mentions)
Rapamycin, by Selleck Chemicals (1 mentions)
Rotenone, by Selleck Chemicals (1 mentions)
Staurosporine, by Selleck Chemicals (1 mentions)
Neferine, by Selleck Chemicals (1 mentions)
Ferrostatin 1, by Selleck Chemicals (1 mentions)
Z vad fmk, by Selleck Chemicals (1 mentions)
Erastin, by Selleck Chemicals (1 mentions)
Liproxstatin 1, by Selleck Chemicals (1 mentions)
Geldanamycin, by Selleck Chemicals (1 mentions)
2 protocols using daurisoline
1
Ferroptosis and Cell Death Induction
2
Daurisoline and HSP90 Inhibitor Protocol
Check if the same lab product or an alternative is used in the 5 most similar protocols
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Daurisoline and HSP90 inhibitor geldanamycin were obtained from Selleck Chemicals (Houston, TX, USA) and dissolved in DMSO. Cells were treated with Daurisoline (0, 1, 2, 5, 10, or 20 μM) or 10 μM geldanamycin for 24 h. Animal experiments applied intragastric administration of 40 mg/kg Daurisoline 2 days a time.
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