Acquisition was done using Siemens Symbia T-16 SPECT-CT, dual head gamma camera, using standard energy Windows for Tc-99 sestamibi [17 (link)]. Image analysis was done using Syngo MI software and a 4 DMSPECT package.
Symbia t16 spect ct
Manufactured by Siemens
Sourced in Germany, United States
The Symbia T16 is a SPECT/CT system manufactured by Siemens. It combines single-photon emission computed tomography (SPECT) and computed tomography (CT) imaging capabilities in a single integrated device. The Symbia T16 is designed to acquire both SPECT and CT data during a single patient examination.
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Lab products found in correlation
6 protocols using symbia t16 spect ct
1
Tc-99 Sestamibi SPECT-CT Imaging Protocol
2
Tc-DMSA Scintigraphy for Kidney Function
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Kidney function was evaluated in the supine position 3 hours after i.v. injection of 50 MBq 99mTc-DMSA (CIS bio international, Gif sur Yvette Cedex, France). An anterior and posterior acquisition with a preset time of 20 minutes using a double-headed gamma camera (Symbia T16 SPECT/CT, Siemens, Erlangen, Germany) equipped with a low-energy, high- resolution collimator, 256 × 256 matrix. Differential renal function was assessed using region-of-interest drawings including the entire kidney, with a geometrical mean calculated from both projections.
3
Whole-Body Gamma Imaging and SPECT/CT Analysis
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In almost all cases the pigs were euthanized in the morning on the day after reinjection of labelled leukocytes and placed in cold environments waiting for the transport together with the living pigs to Aalborg University Hospital as reported previously by [5 (link)]. Whole-body planar gamma imaging was then acquired by a dual-headed gamma camera in Aalborg with a medium-energy parallel-hole collimator and using the 2 energy peaks of 111In: 172 and 245 keV, 15% symmetrical windows, and simultaneous two-plane anterior and posterior whole-body acquisition (500.000 counts in a 256 × 256 matrix for regional and a 256 × 1024 matrix for whole body, zoom 1.0) and supplied with single photon emission computed tomography/high dose computed tomography SPECT/CT using a Symbia T16 SPECT/CT (Siemens Medical Solutions, Hoffman Estates, Illinois, USA). The data were analysed using Philips Medical Systems DICOM Brilliance TM Workspaces, Koninklijke Philips Electronics NV 2007, DA Best, Netherlands. One day prior to the SPECT/CT high dose CT was performed in the PET-Centre of Aarhus with an integrated PET/computed tomography (CT) system (Siemens Biograph True point 64 PET/CT, Siemens, Erlangen, Germany), one bed position spanning 21 cm. The pigs were placed in dorsal recumbence. Initially, a scout view was obtained to secure body coverage from snout to tail.
4
Quantifying 99mTc Downscatter in 166Ho SPECT
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The crosstalk simulation and performance of the image reconstructions were assessed by conducting and comparing phantom studies. A 99mTc line source centered between two 40 × 40 × 10 cm3 slabs of polymethyl methacrylate (PMMA) scatter material and a 6.3-L cylindrical phantom, filled with 50 MBq 99mTc, were scanned on a Siemens Symbia T16 SPECT/CT, recording the clinically used energy windows of both 99mTc (140 keV, 15% width) and 166Ho (81 keV, 15% width), along with two scatter windows centered at 118 keV and 170 keV (widths 12%). The recorded projections of both phantoms were compared with simulated projections of a digital phantom (of equal shape and activity, based on the attenuation CT image of the setup) to assess quantitative accuracy of the 99mTc-downscatter simulations (i.e., the extent to which 99mTc contaminates the 81-keV 166Ho photopeak window). Projections of the 99mTc line source were used to validate the shape of the PSFs corresponding to 99mTc downscatter in the 81-keV energy window.
5
Pretherapeutic Radioiodine Dosimetry Protocol
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The pretherapeutic dosimetry protocol at the Surin Hospital was performed following European Association of Nuclear Medicine (EANM) standard operational procedures (3 (link)). Radioiodine ranging from 74 to 185 MBq was administered to patients. The whole-body data in this protocol were obtained from anterior and posterior conjugate views acquired at 2nd, 6th, 24th, 48th, and 72th hours postadministration. The gamma camera used for imaging was Symbia T16 SPECT/CT (Siemens Medical Solutions USA) and equipped with parallel-hole high energy collimators, using a 10% energy window set at 364 keV. The table speed for the whole-body images was 8 cm/min and the latter were acquired using a 256x1024 matrix. These protocol settings were applied to all patients and time points.
6
Renal Artery Stenosis Evaluation
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The patients’ baseline characteristics, including age, gender, duration of hypertension and diabetes, and stenotic degree of RA were collected. In addition, routine kidney ultrasound examination parameters, such as kidney size, cortex thickness, and hemodynamic parameters, including the main RA peak systolic velocity (PSV), abdominal PSV, interlobar artery PSV, acceleration time, and resistance index were collected from a prospectively maintained RAS Clinical and Imaging Database designed by Medical Research Statistics Center, Fuwai Hospital. Moreover, the features of RA and CBP at 6 months and 12 months follow-up were also recorded. The GFR of each kidney and the total GFR were determined using 99mTc-DTPA renal dynamic imaging using Symbia T16 SPECT/CT (Siemens Company, Germany) at baseline and 12 months after PTRAS.
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