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Coenzyme q4

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Coenzyme Q4 is a lipid-soluble quinone compound that plays a crucial role in the electron transport chain within the mitochondria of cells. It is an essential component of the respiratory system, facilitating the transfer of electrons and contributing to the production of cellular energy in the form of adenosine triphosphate (ATP).

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Lab products found in correlation

Coenzyme q10, by Merck Group (2 mentions) Coenzyme q1, by Merck Group (1 mentions) Butylated hydroxy toluene, by Thermo Fisher Scientific (1 mentions) Ethanol, by Thermo Fisher Scientific (1 mentions) Sodium borohydride nabh4, by Thermo Fisher Scientific (1 mentions) Lc ms grade methanol, by Thermo Fisher Scientific (1 mentions) Chloroform, by Thermo Fisher Scientific (1 mentions) 2 propanol, by Thermo Fisher Scientific (1 mentions) 6n hydrochloric acid hcl solution, by Thermo Fisher Scientific (1 mentions) Coenzyme q9, by Merck Group (1 mentions) Milli q system, by Merck Group (1 mentions) Geranyl acetone, by Merck Group (1 mentions) Palmitoleic acid, by Merck Group (1 mentions) Oleamide, by Merck Group (1 mentions) Farnesol, by Merck Group (1 mentions) Methyl palmitoleate, by Merck Group (1 mentions) Geranylgeraniol, by Merck Group (1 mentions) Vitamin k1, by Merck Group (1 mentions) Palmitoyl ethanolamide, by Merck Group (1 mentions) Benzyl cinnamate, by Merck Group (1 mentions)

3 protocols using coenzyme q4

1

Coenzyme Q Compounds: Detailed Acquisition

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Coenzyme Q1 (C7956, 2,3-Dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-1,4-benzoquinone, Ubiquinone-1, Ubiquinone-5, C14H18O4); Coenzyme Q2, (C8081, 2,3-Dimethoxy-5-methyl-6-geranyl-1,4-benzoquinone, Ubiquinone-10, C19H26O4); Decylubiquinone, (D7911, 2,3-Dimethoxy-5-methyl-6-decyl-1,4-benzoquinone, C19H30O4); Coenzyme Q4 (C2470, 2,3-Dimethoxy-5-methyl-6-(geranylgeranyl)-1,4-benzoquinone, Q-4, Ubiquinone-20, Ubiquinone-4, C29H42O4) and Coenzyme Q10 (C9538, Q-10, Ubiquinone 50, Ubiquinone-10, C59H90O4) were purchased from Sigma-Aldrich. The chemical names of ubiquinones often do not correspond to their commercial names as coenzymes. Therefore, to avoid possible misunderstandings, we use the term coenzyme Q as far as possible.
Čermáková P., Kovalinka T., Ferenczyová K, & Horváth A. (2019). Coenzyme Q2 is a universal substrate for the measurement of respiratory chain enzyme activities in trypanosomatids. Parasite, 26, 17.
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2

Quantification of Coenzyme Q Levels

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LC-MS grade methanol, 2-propanol, 1-propanol, ammonium formate, chloroform and ACS reagent grade hexane, ethanol, butylated hydroxytoluene (BHT), sodium borohydride (NaBH4) and 6 N hydrochloric acid (HCl) solution were obtained from Fisher Scientific (Pittsburgh, PA, USA). Mass spectrometry calibration solutions (Thermo Scientific Pierce LTQ Velos ESI positive and negative ion calibration solutions) were procured from Thermo Fisher Scientific (San Jose, CA, USA). Coenzyme Q4 (purity ≥ 90%), used as an internal standard, coenzyme Q9 (purity ≥ 95% ) and coenzyme Q10 (purity ≥ 98%) were procured from Sigma–Aldrich (St. Louis, MO, USA), Cayman Chemical Company (Ann Arbor, MI, USA), Fisher Scientific, respectively. Ultrapure water was obtained from Milli-Q system (Millipore Co., Billerica, MA, USA).
Pandey R., Riley C.L., Mills E.M, & Tiziani S. (2018). Highly Sensitive and Selective Determination of Redox States of Coenzymes Q9 and Q10 in Mice Tissues: Application of Orbitrap Mass Spectrometry. Analytica chimica acta, 1011, 68-76.
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3

Comprehensive Collection of Lipid Standards

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Balsam of Peru (W211613), balsam of Peru oil (W211710), benzyl cinnamate (234214), benzyl benzoate (B9550), geranylgeraniol (G3278), farnesol (277541), geranylgeranyl acetone (G5048), geraniol (163333), squalene (S3626), geranyl acetone (250716), vitamin K1 (V3501), vitamin K2 (V9378), vitamin A (R7632), vitamin E (T3251), vitamin D3 (C9756), coenzyme Q2 (C8081), coenzyme Q0 (D9150), coenzyme Q4 (C2470), coenzyme Q6 (C9504), coenzyme Q10 (C9538), palmitoleic acid (P9417), methyl palmitoleate (P9667), cis-11-hexadecenal (249084), palmityl acetate (P0260), palmitoleyl alcohol (P1547), lauryl palmitoleate (P1642), oleamide (O2136), palmitoyl ethanolamide (P0359), tetradecanoic acid ethylamide (R425567), N-oleoyl glycin (O9762), N,N-dimethyl tetradecanamide (S347388), and 1-dodecyl-2-pyrrolidinone (335673) were obtained from Sigma-Aldrich (St. Louis, MO). Coenzyme Q1 (270–294-M002) was obtained from Alexis Biochemicals.
Nicolai S., Wegrecki M., Cheng T.Y., Bourgeois E.A., Cotton R.N., Mayfield J.A., Monnot G.C., Nours J.L., Van Rhijn I., Rossjohn J., Moody D.B, & de Jong A. (2020). Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products. Science immunology, 5(43), eaax5430.
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