AACOCF3, an inhibitor of p-cPLA2 (Cayman chemicals, cat# 62120) was used to inhibit the cPLA2 activity and LD biogenesis. MEK inhibitor U0126 (Sigma-Aldrich, cat# U120) was used to inhibit ERK activity. PG545, a heparanase inhibitor, was used to block the effect of extracellular growth factor signaling (Progen pharmaceuticals).
Mek inhibitor u0126
Manufactured by Merck Group
Sourced in United States
MEK inhibitor U0126 is a chemical compound that functions as a selective and potent inhibitor of the mitogen-activated protein kinase kinase (MEK1 and MEK2) enzymes. It is commonly used as a research tool in cell biology and signaling pathway studies.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using mek inhibitor u0126
1
Inhibition of cPLA2, ERK, and Heparanase
2
Investigating Ezh2 and Mek Inhibition
Check if the same lab product or an alternative is used in the 5 most similar protocols
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Cells were treated with 20 μM Mek inhibitor U0126 (Sigma, St Louis, MO, USA), 4, 8 and 16 μM Ezh2 inhibitor GSK126 (Xcess Biosciences, San Diego, CA, USA), and dimethyl sulfoxide carrier (Sigma).
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