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Ml218

Manufactured by Merck Group
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Sourced in Australia

ML218 is a compact and versatile laboratory equipment designed for precise measurement and analysis. It features high-quality sensors and advanced data processing capabilities. The core function of ML218 is to provide accurate and reliable data for scientific research and laboratory applications.

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Lab products found in correlation

Mibefradil, by Merck Group (1 mentions) Nifedipine, by Merck Group (1 mentions) Lomustine, by Merck Group (1 mentions) Vincristine, by Merck Group (1 mentions) Gsk1016790a, by Merck Group (1 mentions) Verapamil hydrochloride, by Merck Group (1 mentions) Mibefradil dihydrochloride hydrate, by Merck Group (1 mentions) Ac1903, by Merck Group (1 mentions) Yoda1, by Merck Group (1 mentions) Ym 58483, by Merck Group (1 mentions) Celltiter fluor cell viability, by Promega (1 mentions) Hc 067047, by Merck Group (1 mentions) Nnc55 0396 hydrate, by Merck Group (1 mentions) Synta66, by Merck Group (1 mentions) Resazurin sodium salt, by Merck Group (1 mentions)

2 protocols using ml218

1

Sensitivity to Trastuzumab in Cancer Cells

Cited 1 time
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Cells were treated with mibefradil (0.01–1 µM; Sigma Aldrich) [33 (link)] or ML218 (0.1–10 µM; Sigma Aldrich) [34 (link)] either alone or in combination with trastuzumab (10 µg/mL), 24 h after seeding (2000 cells/well in a 96 well plate). All treatments and media changes were repeated every 2 days in antibiotic-free media. Sensitivity to trastuzumab was assessed using a MTS assay 192 h after treatment start.
Pera E., Kaemmerer E., Milevskiy M.J., Yapa K.T., O’Donnell J.S., Brown M.A., Simpson F., Peters A.A., Roberts-Thomson S.J, & Monteith G.R. (2016). The voltage gated Ca2+-channel Cav3.2 and therapeutic responses in breast cancer. Cancer Cell International, 16, 24.
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2

Chemical Screening for Cell Viability

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Dimethylsulfoxide (DMSO), Minimum Essential Medium Eagle (EMEM, M0643), sodium bicarbonate (NaHCO3), noble agar (A5431), resazurin sodium salt (199303), Vincristine (V0400000), Lomustine (L5918), YM-58483 (Y4895), Synta66 (SML1949), GSK1016790A (G0798), HC-067047 (SML0143), AC1903 (SML2244), ML218 (SML0385), Mibefradil dihydrochloride hydrate (M5441), NNC55-0396 hydrate (N0287), Yoda1 (SML1558), Verapamil hydrochloride (V4629) and Nifedipine (N7634) were purchased from Sigma-Aldrich (Ryde, NSW, Australia). IA65 was a kind gift from Professor William Denny and Dr. Ralph Stevenson, and was synthesised as previously described [28 (link)]. CellTiter-Fluor™ Cell Viability (G6081) was obtained from Promega (Madison, WA, USA).
Sedeeq M., Maklad A., Gueven N, & Azimi I. (2020). Development of a High-throughput Agar Colony Formation Assay to Identify Drug Candidates against Medulloblastoma. Pharmaceuticals, 13(11), 368.
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