The rats were anesthetized at 2, 4, 6, 8, and 12 weeks after implantation via intraperitoneal injection with a 10% chloral hydrate solution (0.4 ml/100 g), and their thighs were then scanned along the axial plane by computerized tomography (CT, Light Speed 64 slice spiral CT, General Electric, USA, 2.5 mm slice thickness). The position and bone formation in the implants were observed in the CT images, and simultaneously, CT values of the newly formed bone were measured and comparatively analyzed.
Lightspeed 64 slice spiral ct
Manufactured by GE Healthcare
Sourced in United States, United Kingdom
The Lightspeed 64-slice spiral CT is a high-performance computed tomography (CT) imaging system produced by GE Healthcare. It is capable of acquiring 64 slices of image data simultaneously, enabling rapid and comprehensive scanning of the patient's anatomy.
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Lab products found in correlation
4 protocols using lightspeed 64 slice spiral ct
1
In Vivo Bone Formation Monitoring
2
CT Imaging of Vertebral Lesions
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CT imaging was performed using a GE Lightspeed 64-slice spiral CT (GE Medical System, Chalfont St Giles, UK) or a Siemens Somatom Definition Flash dual-source CT (Siemens, Erlangen, Germany). The parameters were 120 kVp, 200–300 mAs; collimator width of 0.625 or 0.60 mm; pitch of 1.0; slice thickness of 2 mm; and interlayer distance of 3 mm.
For each case, 8 imaging features were determined: lesion location, position, vertebral compression, boundary, residual bone crest, “soap bubble sign”, largest diameter, and CT value. These were evaluated by 3 musculoskeletal radiologists, and the consensus results were used. The location of the lesion included the cervical, thoracic, lumbar, and sacral spine. The position was classified according to whether the lesion was located in the vertebral body or vertebral arch. The boundary was classified as clear or unclear. The “soap bubble sign” was defined as the bone cortex having obvious expansive changes compared with the normal vertebra.Figure 2
For each case, 8 imaging features were determined: lesion location, position, vertebral compression, boundary, residual bone crest, “soap bubble sign”, largest diameter, and CT value. These were evaluated by 3 musculoskeletal radiologists, and the consensus results were used. The location of the lesion included the cervical, thoracic, lumbar, and sacral spine. The position was classified according to whether the lesion was located in the vertebral body or vertebral arch. The boundary was classified as clear or unclear. The “soap bubble sign” was defined as the bone cortex having obvious expansive changes compared with the normal vertebra.
3
Preoperative CT Examination Protocol
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All 62 patients received preoperative CT examination before surgery. CT examination was performed on a GE Light speed 64 slice spiral CT (GE Medical System, Chalfont St Giles, UK) or a Siemens Somatom Definition Flash dual-source CT (Siemens, Erlangen, Germany), with tube voltage of 120 kV, tube current of 200–300 mAs. The collimator width was 0.625 and 0.60 mm, respectively; the pitch was 1.0; the slice thickness of reconstruction was 3 mm; the interlayer distance was 3 mm.
4
High-Resolution CT Imaging of Nasal Anatomy
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The CT scanning range spanned from the superior margin of the frontal sinuses to the inferior margin of the maxillary alveolar process. A GE Lightspeed 64-slice spiral CT (USA) system was used with a bone imaging algorithm. CT scans were obtained at a section thickness of 0.625 mm and an interval of 0.5 mm. The following parameters of acquisition were used: 120 kV, 320 mA, collimation 40 × 0.6 mm, tube rotation 1 s, matrix size 512 × 512, and reconstruction thickness 3 mm [7, (link)9] (link).
The GE system was used to obtain multiplanar reconstructions using three anatomical planes. The standard plane of coronal reconstruction requires being perpendicular to the hard palate to minimise the effect of the reconstruction plane on the observations (Fig. 1). An indicator line of reconstruction is shown in Figure 1, and this reconstruction was designed to avoid the excessive forward or backward inclination of the reconstruction plane to affect the appearance of the cell on the coronal plane. GE Centricity Enterprise Web 3 software (GE Medical Systems) was used for viewing and measuring. Continuous observation was performed by sliding the computer mouse. The posterior nasal septum and its adjacent SS and PE were the main structures that were observed.
The GE system was used to obtain multiplanar reconstructions using three anatomical planes. The standard plane of coronal reconstruction requires being perpendicular to the hard palate to minimise the effect of the reconstruction plane on the observations (Fig. 1). An indicator line of reconstruction is shown in Figure 1, and this reconstruction was designed to avoid the excessive forward or backward inclination of the reconstruction plane to affect the appearance of the cell on the coronal plane. GE Centricity Enterprise Web 3 software (GE Medical Systems) was used for viewing and measuring. Continuous observation was performed by sliding the computer mouse. The posterior nasal septum and its adjacent SS and PE were the main structures that were observed.
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