Blood samples were drawn in the morning after an overnight fast for measurement of blood count (including neutrophil and lymphocytes), glycated hemoglobin (HbA1c), total cholesterol (TC), triglycerides (TG), uric acid (UA) and creatinine. Complete blood count and examinations were performed using a Beckman Coulter LH 780 instrument and Bio Majesty JCA-BM 6050 (JEOL, Tokyo, Japan).
NLRs were calculated as the ratio of the absolute neutrophil and lymphocyte counts. Total white blood cells (WBCs), neutrophils and lymphocytes, were obtained from the same automated blood sample. Hypertension was defined as systolic blood pressure (SBP) >140 mmHg, diastolic blood pressure (DBP) >90 mmHg, and/or having received treatment for hypertension. Dyslipidemia was defined as a TC concentration >5.69 mmol/L, a TG concentration >1.70 mmol/L, and/or having received treatment for dyslipidemia.
The estimated glomerular filtration rate (eGFR) was used to estimate kidney function and was calculated as follows [26] : Male: eGFR (mL•min -1 •1.73 m -2 ) = 0.741 × 175 × age -0.203 × (serum creatinine) -1.154 . Female: eGFR = 0.741 × 175 × age -0.203 × (serum creatinine) -1.154 × 0.742.
NLRs were calculated as the ratio of the absolute neutrophil and lymphocyte counts. Total white blood cells (WBCs), neutrophils and lymphocytes, were obtained from the same automated blood sample. Hypertension was defined as systolic blood pressure (SBP) >140 mmHg, diastolic blood pressure (DBP) >90 mmHg, and/or having received treatment for hypertension. Dyslipidemia was defined as a TC concentration >5.69 mmol/L, a TG concentration >1.70 mmol/L, and/or having received treatment for dyslipidemia.
The estimated glomerular filtration rate (eGFR) was used to estimate kidney function and was calculated as follows [26] : Male: eGFR (mL•min -1 •1.73 m -2 ) = 0.741 × 175 × age -0.203 × (serum creatinine) -1.154 . Female: eGFR = 0.741 × 175 × age -0.203 × (serum creatinine) -1.154 × 0.742.