RPMI-1640 with Glutamax, non-essential amino acids (NEAA), sodium pyruvate, and penicillin–streptomycin (P/S) were from Gibco (Paisley, Scotland, UK). Fetal bovine serum (FBS) was purchased from Life Science Production (Barnet, UK). Cytokines M-CSF, IL-4, and IFN-γ were purchased from Biolegend (San Diego, CA, USA). 2-Deoxy-D-glucose (2-DG), Oligomycin (Oligo), Carbonyl cyanide-4-(trifluoromethoxy) phenylhydrazone (FCCP), Rotenone (R/Rot,), and Antimycin A (AA) were purchased from Abcam (Cambridge, UK). Perhexiline (PerHx) and H531 (Hx) were purchased from Tocris (Bristol, UK). CB-839 was purchased from FOCUS Biomolecules (Plymouth Meeting, PA, USA). Trimetazidine (TMZ) was purchased from Sigma-Aldrich (St. Louis, MO, USA). VLX-600 (VLX) was purchased from Cayman Chemical (Ann Arbor, MI, USA). Lipopolysaccharide (LPS) from E. Coli was obtained from Sigma-Aldrich. Any other material used was of analytical grade.
Trimetazidine tmz
Manufactured by Merck Group
Sourced in United States
Trimetazidine (TMZ) is a pharmaceutical compound primarily used in the treatment of angina pectoris. It acts as a metabolic modulator, shifting myocardial energy production from fatty acid oxidation to glucose oxidation, which can improve the efficiency of myocardial oxygen utilization. TMZ is approved for medical use in several countries, including the European Union, for the treatment of stable angina pectoris.
Automatically generated - may contain errors
Lab products found in correlation
Lipopolysaccharide lps from e coli, by Merck Group (1 mentions)
Rpmi 1640 with glutamax, by Thermo Fisher Scientific (1 mentions)
Cb 839, by Focus Biomolecules (1 mentions)
Vlx 600, by Cayman Chemical (1 mentions)
Interleukin 4 (il 4), by BioLegend (1 mentions)
M csf, by BioLegend (1 mentions)
Penicillin streptomycin p s, by Thermo Fisher Scientific (1 mentions)
Ifn γ, by BioLegend (1 mentions)
Alloxan, by Merck Group (1 mentions)
Heparin, by Merck Group (1 mentions)
Ketamine, by Alfasan (1 mentions)
Xylazine, by Alfasan (1 mentions)
2 protocols using trimetazidine tmz
1
Reagents for Macrophage Metabolism Analysis
2
Trimetazidine, Heparin, and Alloxan Protocol
Check if the same lab product or an alternative is used in the 5 most similar protocols
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Trimetazidine (TMZ), heparin and alloxan were obtained from Sigma Chemical Co.
(St. Louis, MO, U.S.A.) and Ketamine and xylazine purchased from Alfasan Co
(Woderen- Holland).
(St. Louis, MO, U.S.A.) and Ketamine and xylazine purchased from Alfasan Co
(Woderen- Holland).
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