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358 protocols using spss v15

1

Robust Statistical Analysis of Mouse Survival

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All the results were expressed as mean ± standard deviation (SD) of three or more replicates. Statistical analysis was performed using Student’s t-tests and one-way ANOVA with post hoc Tukey tests (SPSS v.15, SPSS, Chicago, IL, USA). Mice survival was evaluated with the Kaplan–Meier method. Finally, the log-rank test was used to compare the proportion of living mice between groups. All tests were performed with the Statistical Package for the Social Sciences (SPSS) v. 15.0 software, and differences were considered statistically significant at a p-value < 0.05.
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2

Exploring CSF Biomarkers and Functional Connectivity in AD

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Student’s t tests, chi-square (X2) analyses, and analysis of covariance (ANCOVA) will examine differences in demographic, clinical, neuropsychological, CSF biomarker, and FC measures between the study groups (SPSSv15, SPSS, IL). Partial correlation analyses and linear regression models will examine associations between CSF biomarker levels and FC measures, adjusting for age, gender, and the APOE4 genotype (SPSSv15, SPSS, IL). Bootstrap analyses will compare correlations between CSF biomarker measures (individually or as combinations of markers, using principal components analysis) and FC in the DMN and semantic memory networks in AD and controls (R Statistical Software).
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3

Proteomic Analysis of MDA Modifications

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Data from the analysis of depletion of amino groups and accretion of protein hydrazones, allysine and fluorescent Schiff bases (n = 9 per treatment) in proteins treated with MDA, were collected and subjected to statistical analyses. Normality and homoscedasticity were checked for every data set in order to comply with the ANOVA requirements. In order to assess the effect of MDA addition and incubation time, a two-way analysis of variance (ANOVA) was applied to data (SPSS v. 15.5). In order to assess the effect of MDA dose, a one-way analysis of variance (ANOVA) was applied to data (SPSS v. 15.5). Tukey tests were applied when ANOVA found significant differences among treatments. Correlation coefficients were also calculated to assess potential connections between measurements. The statistical significance was set at p < 0.05.
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4

AAA Gene Expression Analysis

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True replicates (n = 3) were subjected to duplicate analyses and data were collected and subjected to statistical analysis. Earlier, the data were analyzed for normality (Shapiro–Wilk test) and homoscedasticity (Bartlett test). The effects of AAA concentration and incubation times were studied using analyses of variance (ANOVA) (SPSS v. 15.5). The effect of AAA on the gene expression (ΔΔCT values) was analyzed using the paired Students’ t test (SPSS v. 15.5). The statistical significance was set at p ≤ 0.05.
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5

Statistical Analysis of Experimental Data

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Data analysis was performed using a one-way ANOVA with multiple comparisons. Turkey’s post hoc adjustment was utilized to compare multiple groups, using SPSS v15 (IBM; Armonk, New York, USA). A p-value of less than 0.05 was set for statistical significance. Results are shown as mean (M) ± standard error (SE).
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6

Tissue-Specific Enzyme Analysis

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All values were expressed as mean±standard error (SEM). Statistical difference in % MV and AST levels (for each tissue evaluated during 7 and 30 days) were determined by Student’s t-test (Ts). If the assumptions required for this test were not met, we used the nonparametric Mann-Whitney test. Additionally, we performed a Pearson Correlation analysis to associate % MV and AST levels in each A. brevifilis tissue tested. We analyzed all data using SPSS v15 (IBM Corporation, Armonk, New York, USA).
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7

Circumcision Outcomes: A Comprehensive Study

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Data on participant eligibility, procedural success, duration of circumcision, rate of AEs, time to complete healing, need for a dorsal slit, pain scores, time of ring removal/detachment, as well as participant satisfaction with the appearance of the healed penis were collected. AEs were pre-specified according to the WHO Technical Advisory Group on Innovations in Male Circumcision and classified as related or unrelated to circumcision [19 , 20 ]. Moderate and severe AEs were photographed for subsequent review. Complete wound healing was defined as the absence of a scab with a completely epithelialized and dry skin surface based on clinical assessment. Wound healing was assessed at each site by the clinician examining the participant. Time to wound healing was calculated and compared between the different participant groups. χ2, t-test, and Mann-Whitney U test were used for statistical analysis (SPSS v15, IBM Corporation, Armonk, NY). Alpha level for significance was set at 5%. Missing data was not imputed.
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8

Orthostatic Hypotension in PASC Patients

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The analysis was performed with SPSS v 15 (IBM statistics, Armonk, NY). Normal distribution was determined by the Shapiro-Wilk test. Continuous variables were reported as mean ± SD or median, interquartile range (IQ) as appropriate, and categorical variables were reported as number (%). The frequency of EOPR/OHT during HUTT in PASC patients was compared to healthy controls using a Chi-squared test. Comparisons between groups and within the time frame were performed through analysis of variance for repeated measures, according to the group (EOPR/OHT+ vs. EOPR/OHT-). The odd ratio for the presence of EOPR/OHT was adjusted for obesity using logistic regression. The differences were considered statistically significant with a p-value <0.05.
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9

Differentiating Neoplastic and Infective Lesions

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Tests for normality was carried out for all the parameters of APT-w contrast extracted from both ROI-1 and ROI-2 using Shapiro-Wilk’s test. This test was carried out for each group of ICMLs (low grade glioma (LGG), high-grade-glioma (HGG) and infective mass lesions) separately. After normality testing, mean, median, mode and other histogram parameters of APT-w contrast were compared between neoplastic mass lesion and infective mass lesion using Independent Student’s T-test with two tails. Histogram parameters of APT-w contrast were also compared among different groups of ICMLs (LGG, HGG and infective mass lesions) using a One-way analysis of variance (ANOVA) with Tukey’s honestly significant difference (HSD) post-hoc test. While differentiating lesion from contra-lateral region, Independent Student’s T-test was used. The difference was considered statistically significant if p<0.05. Receiver operation characteristics (ROC) analysis was conducted to evaluate the diagnostic performance of the histogram parameters in differentiating neoplastic from infective mass lesion, as well as in differentiating ICMLs. Sensitivity, specificity, area under curve (AUC) with 95% confidence interval (CI), accuracy and cut off were computed in ROC analysis. Statistical analysis was performed with a commercially available software package SPSS.v.15 (IBM SPSS Statistics, v. 15.0; Armonk, NY).
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10

Relapse and GVHD Analysis Protocol

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The demographic and baseline characteristics are presented with descriptive statistics. The comparisons between the variables were made with the Chi-square method. The relapse and GVHD analyses were performed in a competitive risk framework, using the non-parametric estimator of cumulative incidence, and as a time-dependent covariate. The software used was the SPSS.V.15 (IBM Software, USA) and Prisma Software V 6.0.1 (GraphPad software, USA).
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