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Tefluthrin

Manufactured by Santa Cruz Biotechnology
Sourced in United States

Tefluthrin is a synthetic pyrethroid insecticide manufactured by Santa Cruz Biotechnology. It is used as a contact and stomach poison for the control of a variety of insect pests. Tefluthrin acts on the central nervous system of insects, causing paralysis and eventual death. The product is formulated for application in agricultural settings.

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2 protocols using tefluthrin

1

Comparative Analysis of Cell Lines

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Human CCF-STTG1 astrocytoma, human Caco2 epithelial colorectal adenocarcinoma, human HepG2 hepatoma and mouse BV2 microglia cell lines were purchased from ATCC. Immortalized LXR double-knockout (LXRα-/LXRβ-) and LXR expressing (LXRα+/LXRβ-) mouse embryonic fibroblasts (MEFs), previously described [59 (link)], were kindly provided by Dr. Peter Tontonoz (UCLA, CA). Primary human astrocytes and primary human hepatocytes (hHepatocyte) were purchased from ScienCell. Primary human macrophages (hMacrophage) were purchased from STEMCELL (BC, Canada). The LXR agonist GW3965 was provided by Dr. Jon Collins (GlaxoSmithKline, NC). The small molecule screening library from which compound 82879 was identified and from which additional structural analogues were tested was provided by LIMR Chemical Genomics Center (LCGC, Wynnewood, PA). Permethrin was purchased from Sigma-Aldrich (cat #: 45614). Bifenethrin (cat #: N-11203) and cyhalothrin (cat #: N-12307) were purchased from Chem Service (West Chester, PA). Tefluthrin was purchased from Santa Cruz (cat #: sc-236965). Stocks of all compounds were prepared in dimethyl sulfoxide (DMSO).
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2

Analytical Standards for Insecticides

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Analytical standards of Bifenthrin, Tefluthrin, cyfluthrin, and tebupirimphos were used, which were the active ingredients in the formulated soil insecticides tested in the field. Bifenthrin 98%, cyfluthrin 99.2%, and tebupirimphos 97% were obtained from Chem Service Inc. (West Chester, PA, US; Cat. Nos. N-11203/CAS 82657-04-3, N-11130/ CAS 68359-37-5, and N-13503/CAS 96182-53-5, respectively). Tefluthrin ≥95% was provided by Santa Cruz Biotechnology, Inc. (Dallas, TX, US; Cat. No. sc-236965/CAS 79538-32-2). All insecticides were dissolved in acetone ≥99.9% supplied by Sigma-Aldrich Corp. (St. Louis, MO, US; Cat. No. 650501/CAS 67-64-1) for stock solution preparation.
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