12 channel head rf receiver coil

The MRI scans were performed on a 3T Siemens TIM Trio clinical MRI scanner using a body radio-frequency transmission coil with a 12-channel head RF receiver coil (Siemens, Erlangen, Germany). High-resolution anatomical images were acquired using an MP-RAGE sequence (TR/TE/flip angle = 2100 ms/3.1 ms/12°), non-selective inversion pulse, TI = 1100 ms, FOV = 160 x 192 x 192 mm, 1.0 mm isotropic spatial resolution. The anesthetized animal preparation - for optimized physiological stability and functional imaging responses - has been described in previous studies (Szabó et al., 2007 ; Salinas and Szabó, 2015 (link)). Briefly, for each anatomical MRI scan, animals received an injection of intramuscular ketamine (5-10 mg/kg) or diazepam 10 mg for initial sedation, intubation and intravenous catheterization. The baboons were anesthetized with isoflurane 1% (1-1.5 MAC) during acquisition of structural MRI scans. Each animal’s respiration, heart rate and oxygenation were monitored throughout the procedures and in the recovery room. No complications were noted during or after any of the procedures.

The MRI scans were performed on a 3T Siemens TIM Trio clinical MRI scanner using a body radio-frequency transmission coil with a 12-channel head RF receiver coil (Siemens, Erlangen, Germany). Blood-oxygen-level dependent (BOLD) rs-fMRI was acquired using a gradient echo-planar imaging pulse sequence. Whole brain coverage rs-fMRI was acquired parallel to the anterior commissure - posterior commissure line with the following scanning parameters: repetition time (TR) = 3,000 msec, echo time (TE) = 30 msec, acquisition matrix = 124 × 124 mm, spatial resolutions of 1.048 mm × 1.048 mm, and 27 axial slices (slice thickness = 1.9 mm) were acquired for at least five minutes. In the same session, high-resolution anatomical images were acquired using a magnetization-prepared, rapid gradient-echo (MP-RAGE) sequence (TR/TE/flip angle = 2100 ms/3.1 ms/12°), non-selective inversion pulse, TI = 1100 ms, FOV = 160 × 192 × 192 mm, 1.0 mm isotropic spatial resolution. We used the anatomical MRIs for within modality co-registration and spatial normalization.