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Polydioxanone

Manufactured by Evonik
Sourced in Germany

Polydioxanone is a synthetic absorbable polymer used in the manufacture of surgical sutures and other medical devices. It is a homopolymer of p-dioxanone and is known for its strength, flexibility, and ability to gradually degrade in the body over time.

Automatically generated - may contain errors

2 protocols using polydioxanone

1

Polydioxanone-based Biomaterial Fabrication

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Polydioxanone
(Resomer X 206S, inherent viscosity
2.0, Mw = 1.01 × 105 g/mol)
was purchased from Evonik, Germany. KCG and FUC were bought from Sigma-Aldrich.
1,1,1,3,3,3-hexafluoroisopropanol (HFIP) purchased from FluoroChem,
was used as received. The Milli-Q water used in this study was drawn
from a Millipore Direct Q8 system (Millipore, Schwalbach, with Millimark
Express 40 filter, Merck, Germany) with a resistivity of 18.0 MΩ
cm. Phosphate buffer tablets (PBS) were purchased from VWR Life Sciences
and PBS solution was prepared by dissolving one tablet in 100 mL of
Milli-Q water.
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2

Fabrication of Biocompatible Scaffolds

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Poly(caprolactone) (50,000 MW) was purchased from Polysciences, Inc. Poly(dioxanone) was purchased from Evonik Inc. 1,1,1, 3, 3, 3, Hexafluoro-2-propanol (HFP) and 2,2’ Trifluoroethanol (TFE) were purchased from Sigma Aldrich and Alfa Aesar respectively. Calcium chloride was obtained from Sigma-Aldrich. Fresh whole pig blood was collected from the UIUC Meat Science Lab in citrate anticoagulant-treated tubes. Simulated Intestinal Fluid (SIF) USP test solution was purchased from VWR.
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