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Methoctramine

Manufactured by Adooq
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Sourced in China

Methoctramine is a chemical compound commonly used in laboratory settings. It serves as a pharmacological tool for researchers to study the function and properties of various biological systems.

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Lab products found in correlation

Z guggulsterone, by Santa Cruz Biotechnology (2 mentions) Jte 013, by Merck Group (2 mentions) Deoxycholic acid, by Merck Group (1 mentions) Ketoconazole, by MedChemExpress (1 mentions) Kg 501, by MedChemExpress (1 mentions) Srebp2 antibody, by R&D Systems (1 mentions) Fatostatin, by MedChemExpress (1 mentions) Lovastatin, by MedChemExpress (1 mentions) Vancomycin, by Selleck Chemicals (1 mentions) Deoxycholic acid dca, by Merck Group (1 mentions) Sr11302, by Apexbio (1 mentions) Ski 606, by Selleck Chemicals (1 mentions)

2 protocols using methoctramine

1

Molecular Regulators of Lipid Metabolism

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Deoxycholic acid and JTE-013 were obtained from Sigma-Aldrich (St. Louis, MO, USA). Triamterene, 4-DAMP, ketoconazole, lovastatin, KG-501 and fatostatin were purchased from MedChemexpress (Monmouth Junction, NJ, USA). Methoctramine was from AdooQ Bioscience (Nanjing, China). Z-Guggulsterone was from Santa cruz Biotechnology (Santa cruz, CA, USA). SREBP2 antibody was obtained from R&D Systems (Minneapolis, MN, USA).
Li D., Zhou J., Wang L., Gong Z., Le H., Huang Y., Xu C., Tian C., Cai W, & Wu J. (2023). Gut microbial metabolite deoxycholic acid facilitates Th17 differentiation through modulating cholesterol biosynthesis and participates in high-fat diet-associated colonic inflammation. Cell & Bioscience, 13, 186.
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2

Signaling Pathway Inhibition Protocol

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Deoxycholic acid (DCA) and JTE-013 were purchased from Sigma-Aldrich (St. Louis, MO). Z-Guggulsterone was purchased from Santa cruz Biotechnology (Santa cruz, CA). Phospherylated and total ERK, JNK, IκB antibodies and SP600125, SB 203580, U0126 were purchased from Cell Signaling Technologies (Beverly, MA). Vancomycin, QNZ and SKI-606 were obtained from Selleckchem (Houston, TX). Methoctramine was purchased from AdooQ Bioscience (Irvine, CA). SR 11302 was purchased from APExBIO (Houston, TX). C29 was obtained from MedChemExpress (Monmouth Junction, NJ). TLR2, Src antibodies were from Abcam and phosphotyrosine antibody (4G10) was from Millipore. ELISA Kits were obtained from eBioscience (San Diego, CA).
Wang L., Gong Z., Zhang X., Zhu F., Liu Y., Jin C., Du X., Xu C., Chen Y., Cai W., Tian C, & Wu J. (2020). Gut microbial bile acid metabolite skews macrophage polarization and contributes to high-fat diet-induced colonic inflammation. Gut Microbes, 12(1), 1819155.
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