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1 1 carbonylbis 1h imidazole

Manufactured by Merck Group
Sourced in United States

1,1'-carbonylbis-1H-imidazole is a chemical reagent used in organic synthesis. It serves as a coupling agent, facilitating the formation of amide bonds between carboxylic acids and amines. The product is a white to off-white crystalline solid.

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2 protocols using 1 1 carbonylbis 1h imidazole

1

Synthesis of Dox-Loaded γ-PGA Nanoparticles

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The γ-PGA (acid form, 50 kDa) was obtained from Bioleaders Corporation (Daejeon, Republic of Korea). Cholesteryl chloroformate, 1,1′-carbonylbis-1H-imidazole (CDI), and ethylenediamine (EDA) were purchased from Sigma-Aldrich Co (St Louis, MO, USA). Doxorubicin hydrochloride (Dox) was obtained from Boryung Pharmaceutical Co (Ansan, Republic of Korea).
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2

Synthesis and Functionalization of γ-PGA

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Poly-(γ-glutamic acid) (γ-PGA; molecular weight =50 kDa) was provided by BioLeaders Corporation (Daejeon, Republic of Korea). Cholesteryl chloroformate (97%), 1,1′-carbonylbis-1H-imidazole, 1,2-ethanediamine, and polyinosinic–polycytidylic acid sodium salt, poly-(I:C), were purchased from Sigma-Aldrich (St Louis, MO, USA). IRDye800 NHS ester was purchased from Li-COR Biosciences (Lincoln, NE, USA).
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