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Balb cj h 2kd

Manufactured by Jackson ImmunoResearch

BALB/cJ (H-2Kd) is a mouse strain that expresses the H-2Kd major histocompatibility complex (MHC) class I molecule. This strain is commonly used in immunology research to study immune responses and interactions involving the H-2Kd antigen.

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4 protocols using balb cj h 2kd

1

Mouse Models for Gal-3 Knockout T Cell Studies

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B6 (H-2Kb), C3H.SW (H-2Kb), NSG-HLA-A2-HHD, and BALB/cJ (H-2Kd) mice were purchased from the Jackson Laboratory. The Galectin-3 knockout (Gal-3−/−) B6 mice were provided by Dr. Fu-Tong Liu through Dr. Noorjahan Panjwani, Tufts University, Boston MA. Gal-3−/− and WT littermates were used as donor T cell sources. All mice were maintained in the Roswell Park Comprehensive Cancer Center (Roswell Park) Lab Animal Shared Resource (LAR) at the standard temperature (~22°C) in specific-pathogen-free housing. Both male and female mice of age 6-8 weeks were used for experiments and were randomly assigned to experimental groups prior to irradiation. All in vivo experiments were performed following the Institutional Animal Care and Use Committee (IACUC)-approved protocol according to Roswell Park animal care guidelines.
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2

Murine Tumor Immunotherapy Protocols

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BALB/cJ (H-2kd) and C57Bl/6J (H-2kb) mice were purchased from the Jackson Laboratory (Sacramento, CA). Firefly Luciferase (Luc)+ transgenic C57BL/6 L2G85 mice have been described previously (19 (link)) and were bred in our animal facility at Stanford University. B6.129S4-Tnfrsf4tm1Nik/J OX40 knockout mice (OX40−/− C57BL/6) were kindly provided by Dr. Ronald Levy’s laboratory at Stanford University.
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3

Transgenic Mouse Strains for Research

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BALB/cJ (H-2Kd) and FVB/NJ (H-2Kq) mice were purchased from the Jackson Laboratory (Sacramento, CA). Firefly Luciferase (Luc+) transgenic FVB/N mice have been previously reported (23 (link)) and were bred in our animal facility at Stanford University. BALB/c Rag1−/−gamma-chain−/− and BALB/c BATF3−/− mouse strains were kind gifts of Dr. Irving Weissman and Dr. Samuel Strober respectively and were bred in our animal facility at Stanford University. All procedures performed on animals were approved by Stanford University’s Institutional Animal Care and Use Committee and were in compliance with the guidelines of humane care of laboratory animals.
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4

Transgenic Mouse Strains for Research

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BALB/cJ (H-2Kd) and FVB/NJ (H-2Kq) mice were purchased from The Jackson Laboratory. Firefly Luciferase (Luc+) transgenic FVB/N mice have been reported previously (23 (link)) and were bred in our animal facility at Stanford University. BALB/c Rag1−/−gamma-chain−/− and BALB/c BATF3−/− mouse strains were kind gifts of Dr. Irving Weissman and Dr. Samuel Strober, respectively, and were bred in our animal facility at Stanford University. All procedures performed on animals were approved by Stanford University's Institutional Animal Care and Use Committee and were in compliance with the guidelines of humane care of laboratory animals.
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