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B6.129p2 fcgr3tm1jsv 2j

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The (B6.129P2-Fcgr3tm1Jsv/2J) is a mouse strain with a targeted mutation in the Fcgr3 gene, which encodes the Fc gamma receptor III. The core function of this strain is to facilitate research on the role of Fc gamma receptor III in immune responses and related biological processes.

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Lab products found in correlation

B6.129s7 ifngtm1ts j, by Jackson ImmunoResearch (2 mentions) Pmel 1 thy1.1 mice b6 cg thy1a cy tg tcratcrb 8rest j, by Jackson ImmunoResearch (2 mentions) B6.129s4 ifngtm3 1lky j, by Jackson ImmunoResearch (2 mentions) B6.129s c batf3tm1kmm j, by Jackson ImmunoResearch (2 mentions)

2 protocols using b6.129p2 fcgr3tm1jsv 2j

1

Mouse Strains for Immunological Studies

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Wild-type C57BL/6J mice, Batf3−/− mice (B6.129S(C)-Batf3tm1Kmm/J), Fcgr3−/− mice (B6.129P2-Fcgr3tm1Jsv/2J), Pmel-1/Thy1.1 mice (B6.Cg-Thy1a/Cy Tg(TcraTcrb)8Rest/J), Ifng−/− mice (B6.129S7-Ifngtm1Ts/J) and IFN-γ reporter mice (B6.129S4-Ifngtm3.1Lky/J) were purchased from the Jackson Laboratory. Tyr:Cre-ER+, LSL-BrafV600E, Ptenfl/fl, R26-LSL-SIY mice (designated BP-SIY) were generated by S. Spranger (MIT) and T. F. Gajewski (University of Chicago) from mouse strains obtained from L. Chin, M. MacMahon, and T. Mak. Mice used in studies were females at 8–10 weeks of age, except that BP-SIY mice were used at 6–14 weeks and both male and female mice were used. They were housed on a 12 hr light/dark cycle at 23°C with food and water ad libitum and were randomly assigned to experimental groups. All animal work was conducted under the approval of the Massachusetts Institute of Technology (MIT) Division of Comparative Medicine in accordance with federal, state and local guidelines.
Wang C., Cui A., Bukenya M., Aung A., Pradhan D., Whittaker C.A., Agarwal Y., Thomas A., Liang S., Amlashi P., Suh H., Spranger S., Hacohen N, & Irvine D.J. (2021). Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade. Cell reports, 37(8), 110021.
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2

Mouse Strains for Immunological Studies

Check if the same lab product or an alternative is used in the 5 most similar protocols
Wild-type C57BL/6J mice, Batf3−/− mice (B6.129S(C)-Batf3tm1Kmm/J), Fcgr3−/− mice (B6.129P2-Fcgr3tm1Jsv/2J), Pmel-1/Thy1.1 mice (B6.Cg-Thy1a/Cy Tg(TcraTcrb)8Rest/J), Ifng−/− mice (B6.129S7-Ifngtm1Ts/J) and IFN-γ reporter mice (B6.129S4-Ifngtm3.1Lky/J) were purchased from the Jackson Laboratory. Tyr:Cre-ER+, LSL-BrafV600E, Ptenfl/fl, R26-LSL-SIY mice (designated BP-SIY) were generated by S. Spranger (MIT) and T. F. Gajewski (University of Chicago) from mouse strains obtained from L. Chin, M. MacMahon, and T. Mak. Mice used in studies were females at 8–10 weeks of age, except that BP-SIY mice were used at 6–14 weeks and both male and female mice were used. They were housed on a 12 hr light/dark cycle at 23°C with food and water ad libitum and were randomly assigned to experimental groups. All animal work was conducted under the approval of the Massachusetts Institute of Technology (MIT) Division of Comparative Medicine in accordance with federal, state and local guidelines.
Wang C., Cui A., Bukenya M., Aung A., Pradhan D., Whittaker C.A., Agarwal Y., Thomas A., Liang S., Amlashi P., Suh H., Spranger S., Hacohen N, & Irvine D.J. (2021). Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade. Cell reports, 37(8), 110021.
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