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Stata se v 14

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Stata/SE V.14 is a statistical software package developed by StataCorp. It provides a wide range of data management, analysis, and visualization tools for researchers and professionals. The software is designed to handle large and complex datasets, offering advanced statistical methods and modeling capabilities.

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93 protocols using stata se v 14

1

Pilot RCT of Recruitment Parameters

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The trial was set up as a small pilot RCT without a defined primary outcome, and hence without a usual power calculation to determine sample size. Instead, sample size was determined to be adequate to estimate the parameters to be tested.26 (link) Based on available data, it was anticipated that the 12 EDs would recruit approximately one participant per month, that is, 108 participants over 9 months.
All statistical analyses were documented a priori in a Statistical Analysis Plan (available from https://www.icnarc.org/Our-Research/Studies/Fish/Study-Documents). Statistical analyses were based on the intention-to-treat principle. All tests used were two-sided with significance levels set at p<0.05 and with no adjustment for multiplicity. Final analyses were conducted using Stata/SE V.14.0.
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2

Doctors' Geographic Location and Student Characteristics

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Chi-squared tests compared univariate associations between the three groups (defined as per 1), adjusting for key student characteristics (calculated as odds ratios (ORs)). A multinomial logistic regression model explored associations between doctors working in metropolitan, large regional (≥50 000 population) or smaller regional/rural (<50 000 population) towns and the six groups of interest (A-E compared to group F in Table 1), adjusting
for key student characteristics that may potentially confound associations (calculated as relative risk ratios because the outcome has three levels). Sensitivity analyses using 2016 work location outcomes were also undertaken. StataSE v14.0 (StataCorp; https://www.stata.com) was used for all statistical analyses and p<0.05 was considered statistically significant.
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3

Diarrhea Treatment Efficacy Trial

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Analyses were performed using SPSS V.25 and STATA/SE V.14.0. The baseline characteristics of the groups were summarised as mean (SD) and median (IQR) by trial arm.
Primary analysis was conducted on an intention-to-treat basis. For the primary outcome, unadjusted and adjusted (baseline characteristics [age and gender], duration of diarrhoea before randomisation, symptoms, use of medication at baseline and study site), Cox regression was used to compare groups and the time (hours) from randomisation to first non-watery stool (soft or firm). The number needed to treat was calculated.
For the secondary outcomes, continuous data were compared using independent t-tests or Mann-Whitney U test (MW). Analysis of covariance (ANCOVA) was used to adjust for baseline characteristics. Categorical data were compared initially using χ2 or Fisher’s exact test and adjusted logistic regression models with ORs and 95% CIs. A p value of <0.05 was considered to indicate statistical significance. Safety analysis included all subjects who were randomised to the study and was based on the treatment received.
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4

Targeted Admissions Strategies Analysis

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We used Stata SE v. 14.0 (StataCorp, 2015, College Station, TX) to perform all statistical analyses, calculating descriptive statistics on targeted admissions strategies. Chi-square tests for independence were used to examine differences in school characteristics by each targeted admissions strategy. The significance level was set at P<.05. "Don't know," "Not applicable," and no responses were coded as missing values and excluded from the denominator when calculating percentages for each target group.
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5

Phylogenetic and Genomic Analyses of Bacterial Strains

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For phylogenetic and sequence analyses, nucleotide sequences obtained from PCR products were corrected and assembled if necessary with SerialCloner2-6 (http://serialbasics.free.fr/Serial_Cloner.html) and 4peaks (http://nucleobytes.com/4peaks/). Sequences were aligned with the ClustalW algorithm (Chenna et al., 2003 (link)) in MEGA 6.0 (Tamura et al., 2013 (link)). Randomized Axelerated Maximum Likelihood (RAxML) (Stamatakis, 2014 (link)) or MEGA 6.0 (Tamura et al., 2013 (link)) were used for the construction of phylogenetic trees. Phylogenetic trees were visualized with FigTree v.1.4.3 (http://tree.bio.ed.ac.uk/software/figtree/) and edited with Adobe Illustrator CS5 (Adobe Systems, San José, CA, USA). In order to study genomic identity among strains, Average Nucleotide Identity (either based on MUMmer alignments, ANIm, or based on BLAST alignments, ANIb) was calculated with the JSpeciesWS online server (Richter et al., 2016 (link)). A distance dendrogram was generated by hierarchical cluster analysis of 100−% ANI matrices (Chan et al., 2012 (link)) with StataSE v.14.0 (StataCorp, College Station, TX, USA) after computation of Euclidean distances with the Average Linked method.
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6

Epidemiological Analysis of Occupational TB

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Descriptive statistics (e.g., frequencies, proportions, means, and standard deviations) of all sociodemographic characteristics by category of job-related exposure were estimated. In addition, we examined other measures of possible TB exposure by category of job-related TB exposure. We conducted bivariate analyses to examine differences between groups using both the chi-square test and the nonparametric Kruskal-Wallis test. All statistical analyses were performed using Stata/SE v. 14.0 (StataCorp, 2015 ).
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7

End-of-Life Preferences among Older Adults

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Descriptive statistics (Table 1) and estimated proportions (Figure 1) were weighted using calibrated cross-sectional weights provided by SHARE (Malter & B€ orsch-Supan, 2017) to make them representative of the target population. Separate multivariate logistic regressions were performed for each EOL attribute (0¼not important/not so important; 1¼important/very important) to determine their association with respondents' personal characteristics and the linguistic region in which they live. Analyses were conducted using Stata SE v.14.0 software (StataCorp, College Station, TX, USA). Estimated standard errors were adjusted for potential unobserved dependencies between partners' responses. Results of the full logistic regression models are presented in Annex 2 in the Supplementary Material. The figures of the result section below present the predicted margins (i.e. standardized proportions adjusting for all of the other model covariates) for a specific characteristic (e.g., gender) across the 23 multivariate logistic regression models. Finally, the value 1 on the outcomes corresponds to both answer categories, "important" and "very important", but we will refer to them collectively as "important" in the following paragraphs.
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8

Comprehensive HIV Knowledge Assessment

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The data were analysed using STATA/SE V.14.0. For the outcome variable (comprehensive HIV knowledge) percentage with a 95% CI was calculated. The intraclass correlation coefficient was found to be statistically significant, hence multilevel mixed-effect logistic regression model was used for the final analysis. Cluster-ID was considered a random component. Initially, a bivariate analysis was done, and conceptually relevant covariates were included in the multivariable analysis. Association was described using an OR with 95% CIs, and statistical significance was declared at p<0.05. Appropriate weighting was done to account for the complex survey design and analysis.
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9

Analyzing Dairy Worker Tuberculosis Risk

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Both chi-square and the non-parametric Kruskal–Wallis tests were conducted to explore potential sociodemographic differences between Dairy A and Dairy B. Corresponding p-values are shown in Table 1. Summary statistics of demographic characteristics of dairy workers with T-SPOT.TB test were reported. Both Fisher's exact test and the non-parametric Kruskal–Wallis tests were conducted to evaluated the association between age, sex, ethnicity, country of birth, category of cattle exposure, and history of BCG vaccine and positive T-SPOT.TB test results on Dairy A and Dairy B. Because all positive T-SPOT.TB test results in this study were derived from foreign-born dairy workers, statistical analysis resulted in foreign-born being a perfect predictor for a positive T-SPOT.TB test result. Therefore, further logistic regression analyses could not be conducted. A type I error level of 0.05 was used to declare significance. Statistical analyses were performed using Stata/SE v.14.0 (23 ).
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10

Statistical Software for Data Analysis

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Analyses were conducted using STATA/SE, v14.0 (StataCorp, College Station, TX).
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