Optics spectrometer

General Methods. All reactions were carried under argon atmosphere. DMF, acetone, THF, toluene, MeCN and acetic acid were used as received from Sigma Aldrich. CH 2 Cl 2 was dried using a dry solvent station GT S100 system. NMR Spectra (1H, 13C) were performed at 298 K. 1H (500 MHz or 300 MHz) and 13C (125 MHz) NMR chemical shifts are reported relative to internal TMS (δ = 0.00 ppm) or to residual protiated solvent. Data are presented as follows: chemical shift (ppm), multiplicity (s = singlet, d = doublet, t = triplet, q = quartet, sept = septet, m = multiplet, br = broad), coupling constant J (Hz) and integration. HRMS data were recorded on a microTOF spectrometer equipped with an orthogonal electrospray (ESI) interface. Thin layer chromatography was performed using Merck TLC silica gel 60 F254 aluminium sheets using petroleum ether/EtOAc or CH 2 Cl 2 /acetone as eluant and visualized using permanganate stain, ninhydrin stain, vanillin stain and/or UV light. Merck Geduran® 40-63 μm silica gel was used for column chromatography. Infrared spectra were reported in frequency of absorption using Alpha Bruker Optics spectrometer.