Active caspase 3 9661

Manufactured by Cell Signaling Technology

Active Caspase-3 (9661) is a lab equipment product that detects the active form of Caspase-3, a key enzyme involved in apoptosis, or programmed cell death. This product can be used to monitor cellular apoptosis in various experimental systems.

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Lab products found in correlation

Caspase 3 9662, by Cell Signaling Technology (1 mentions) Actin a5441, by Merck Group (1 mentions) Etoposide, by Merck Group (1 mentions) Huwe1 a300 486a, by Fortis Life Sciences (1 mentions) Acetyl histone h3, by Merck Group (1 mentions) Jmjd1a 12835 1 ap, by Proteintech (1 mentions) Ki 67 ab8191, by Abcam (1 mentions)

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Caspase-3 (2138 citations) Active caspase-3 (63 citations) Caspases (2 citations)

2 protocols using active caspase 3 9661

Western Blot Analysis of Apoptosis Markers

Cited 1 time

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Western blotting was performed as previously described^{38 (link)}. Primary antibodies, against Caspase-3 (9662), active Caspase-3 (9661), Caspase-6 (9762), active Caspase-6 (9761), Caspase-7 (9492), active Caspase-7 (8438), JNK (9252), p-JNK (9255), NF-κB (8242), p-NF-κB (3033), p38 (8690), p-p38 (4631), p-MK2 (3007), MKK3 (8535), MKK6 (8550), p-MKK3/6 (12280), were purchased from Cell Signaling Technologies (Danvers, MA).

Shang N., Bank T., Ding X., Breslin P., Li J., Shi B, & Qiu W. (2018). Caspase-3 suppresses diethylnitrosamine-induced hepatocyte death, compensatory proliferation and hepatocarcinogenesis through inhibiting p38 activation. Cell Death & Disease, 9(5), 558.

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Antibody Sources for DNA Damage Research

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Antibodies were purchased from the following companies: JMJD1A (12835-1-AP) was from Proteintech (Rosemont, IL). HUWE1 (A300-486A) was from Bethyl Laboratories (Montgomery, TX). RNF8 (sc-271462), BRCA1 (sc-6954), p300 (sc-585), ubiquitin (sc-6085), GFP (sc-8334), HA (sc-7392) and c-Myc (sc-789, sc-40) were from Santa Cruz Biotechnology (Dallas, TX). c-Myc (ab56), PRKDC (ab32566) and Ki67 (ab8191) were from Abcam (Cambridge, UK). NBS1 (3002), p-ATM (4526), ATM (2873), p-Chk2 (2197), Chk2 (2662), XRCC6 (4588), and active caspase-3 (9661) were from Cell Signaling (Danvers, MA). γ-H2AX (05-636), ubiquitin (FK2, ST1200), 53BP1 (MAB3802), Rad51 (ABE257), H3K9me2 (07-441) and acetyl-histone H3 (06-599) were from EMD Millipore (Burlington, MA). Flag (F7425, F3165) and actin (A5441) were from Sigma-Aldrich (St. Louis, MO). Etoposide was from Sigma-Aldrich (St. Louis, MO). Olaparib was from MedChemExpresss (Monmouth Junction, NJ).

Fan L., Xu S., Zhang F., Cui X., Fazli L., Gleave M., Clark D.J., Yang A., Hussain A., Rassool F, & Qi J. (2020). Histone demethylase JMJD1A promotes expression of DNA repair factors and radio-resistance of prostate cancer cells. Cell Death & Disease, 11(4), 214.

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