Plasma and hippocampal samples were prepared for metabolomics analysis as previously described [12 (link)]. Targeted metabolomics measurements were performed at the Mass Spectrometry Core of Beth Israel Deaconess Medical Center, Harvard Medical School (Boston, MA, USA) as previously described [25 (link)] using a 550 QTRAP triple quadrupole mass spectrometer (AB/Sciex, Framingham, MA, USA) coupled to a Prominence UFCL HPLC system (Shimadzu, Columbia, MD, USA). The platform used is based on SRM of selected metabolites as previously outlined [10 (link)].
Prominence ufcl hplc system
Manufactured by Shimadzu
Sourced in United States
The Prominence UFCL HPLC system is a high-performance liquid chromatography (HPLC) instrument manufactured by Shimadzu. It is designed to provide efficient and reliable separation, identification, and quantification of chemical compounds in complex mixtures. The system features an ultra-fast control loop (UFCL) technology, which enables rapid analysis and enhances productivity in laboratory settings.
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Lab products found in correlation
2 protocols using prominence ufcl hplc system
1
Targeted Metabolomics of Plasma and Hippocampus
2
Metabolomics Analysis of G72Tg Hippocampi
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Sample preparation for metabolomics of G72Tg and WT hippocampi (n = 6 per group) was performed as previously described [16 (link),17 (link)]. Samples were measured with a 5500 QTRAP® triple quadrupole mass spectrometer (AB/SCIEX, Framingham, MA, USA) which was coupled to a Prominence UFCL HPLC system (Shimadzu, Columbia, MD, USA) at the Mass Spectrometry Core of Beth Israel Deaconess Medical Center, Harvard Medical School (Boston, MA, USA), using a selected reaction monitoring (SRM)-based platform [18 (link)].
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