Aquilion one genesis edition

Manufactured by Canon

Sourced in Japan

The Aquilion ONE GENESIS Edition is a computed tomography (CT) imaging system designed for diagnostic and clinical applications. It utilizes advanced technologies to capture high-quality images of the human body. The system's core function is to provide healthcare professionals with detailed information about the internal structures and functions of the body, enabling them to make informed medical decisions.

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Lab products found in correlation

Aquilion one, by Canon (2 mentions) Aquilion 64, by Canon (2 mentions) Aquilion one vision edition, by Canon (2 mentions) Aidr 3d, by Canon (2 mentions) Ultravist, by Bayer (1 mentions) Aquilion precision, by Canon (1 mentions) Nitropen, by Nippon Kayaku (1 mentions) Iomeron 350, by Eisai (1 mentions) Vitrea, by Canon (1 mentions) Revolution ct, by GE Healthcare (1 mentions)

14 protocols using aquilion one genesis edition

Standardized Lower Extremity CT Angiography

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All scans were performed on a 320-row-detector CT scanner (Aquilion One GENESIS Edition, Canon Medical Systems Corporation, Japan). The scan was performed from the distal abdominal aorta to the toes in a craniocaudal direction.
Ninety milliliters of iodinated contrast agent (370 mgI/mL, Iopromide, Ultravist, Bayer Health care, Germany) at a flow rate of 4 mL/second was administered intravenously. A region of interest (ROI) was placed on the distal abdominal aorta. When the predefined threshold of 150 HU was reached, 6 s later the scan automatically initiated.
The scanning parameters included slice collimation: 80 × 0.5 mm, rotation time: 0.75 s, pitch: 0.637, automatic modulation tube current: 40–200 mA (with noise index SD = 10), and tube voltage: 100 kVp.
The volumetric CT dose index (CTDIvol) and dose-length product (DLP) were automatically saved for each examination. The effective radiation dose was estimated using the DLP multiplied by the conversion factor of 0.0058 at 100 kV reported by Saltybaeva et al. [15 (link)].

Zhang D., Mu C., Zhang X., Yan J., Xu M., Wang Y., Wang Y., Xue H., Chen Y, & Jin Z. (2023). Image quality comparison of lower extremity CTA between CT routine reconstruction algorithms and deep learning reconstruction. BMC Medical Imaging, 23, 33.

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Adrenal Tumor Screening Using Contrast-Enhanced CT

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Contrast-enhanced CT images were obtained before AVS using a 64-row detector scanner (Aquilion 64; Canon Medical Systems, Otawara, Japan) or a 320-row detector scanner (Aquilion One or Aquilion One GENESIS Edition; Canon Medical Systems). The screening of adrenal tumors was conducted at the following settings: a 1:1 table pitch; collimation, 0.5-1 mm; reconstruction thickness/interval, 1.0 mm/1.0 mm; 100-120 kVp with automatic exposure control; and adaptive iterative dose reduction (AIDR) [20] . After injecting the contrast medium for 30 s, three-phase images were obtained after 45 s, 55 s, and 180 s. The first and second phases' scan ranges were the upper abdomen, while the third phase covered the abdomen and pelvis. The total iodine dose was 600 mg/kg (maximum amount, 45 g). The median interval between CT and AVS was 62 days (range, 1-1281 days).

Morita S., Yamamoto T., Kamoshida K., Yamazaki H., Yatabe M., Ichihara A, & Sakai S. (2021). High Deep Femoral Artery Bifurcation Can Disturb Safe Femoral Venous Access: CT Assessment in Patients Who Underwent Femoral Venous Access Under Doppler Ultrasound Guidance. Interventional Radiology, 6(2), 29-36.

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Coronary CT Angiography with 320-row Scanner

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All patients underwent CCTA with a 320-row computed tomography (CT) scanner (Aquilion ONE ViSION Edition or Aquilion ONE GENESIS Edition; Canon Medical Systems, Otawara, Japan). CT images were acquired at a tube voltage of 100 kVp or 120 kVp depending on body weight (120 kVp for body mass index [BMI] ≥ 30 kg/m²) [16 (link)]. The tube current was calculated by automatic exposure control (target standard deviation = 22). For the 320-row CT, the detector collimation was 320 × 0.5 mm and gantry rotation time was 275 ms. The field of view was adjusted to encompass only the heart. The craniocaudal range was between 240 rows (12 cm) and 320 rows (16 cm) to include the entire coronary tree. As the contrast agent, iomeprol (Iomeron® 350 mg I/mL; Eisai, Tokyo, Japan) was injected for 12 s at 18 mg I/kg/s (Dual Shot GX 7; Nemoto Kyorindo, Tokyo, Japan), followed by 30 mL of saline at the same injection rate [17 (link)]. Using bolus tracking, scanning was started when the CT attenuation value in the ascending aorta reached 300 Hounsfield units (HU). All patients underwent prospective electrocardiogram-gated CCTA.

Inage H., Tomizawa N., Otsuka Y., Aoshima C., Kawaguchi Y., Takamura K., Matsumori R., Kamo Y., Nozaki Y., Takahashi D., Kudo A., Hiki M., Kogure Y., Fujimoto S., Minamino T, & Aoki S. (2022). Use of a deep-learning-based lumen extraction method to detect significant stenosis on coronary computed tomography angiography in patients with severe coronary calcification. The Egyptian Heart Journal, 74, 43.

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Standardized Craniocervical CTA Imaging Protocol

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All scans were performed using a 320-row-detector CT scanner (Aquilion ONE Genesis Edition, Canon Medical Systems, Otawara, Japan). Patients were positioned supine with their arms placed at their sides and instructed not to move their heads during the examination.
The scan range was from the aortic arch to the skull. The monitoring trigger for the contrast scan was positioned at the level of the thoracic aorta with a threshold value of 180 Hounsfield unit. A high-pressure syringe with a double cylinder was used to inject 55 mL of the contrast agent, Ultravist (370 mg I/mL), and 25 mL of saline at a rate of 4 mL/s through the right median cubital vein. Bolus tracking was triggered to start the arterial-phase scanning. Delayed-phase imaging was performed 90 s after contrast medium injection. The scanning parameters were as follows: tube voltage 100 kVp, intelligently and automatically modulated tube current, rotational speed 0.5 s/r, the noise index (standard deviation [SD]) set to 7.5, display-field of view (D-FOV) 300 (M), collimation of 0.5 × 160, matrix size of 512 × 512, and pitch of 0.8.
The CT dose index volume (CTDIvol; mGy) and dose-length product (DLP; mGy·cm) were recorded from the CT scanner. The effective radiation dose (mSv) was calculated as the product of the DLP and a conversion factor of 0.0048 mSv/(mGy·cm) for craniocervical CTA [17 (link)].

Su T., Zhang Z., Chen Y., Wang Y., Li Y., Xu M., Wang J., Li J., Tian X, & Jin Z. (2024). Dark-Blood Computed Tomography Angiography Combined With Deep Learning Reconstruction for Cervical Artery Wall Imaging in Takayasu Arteritis. Korean Journal of Radiology, 25(4), 384-394.

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Dynamic Contrast-Enhanced CT Imaging Protocol

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A 320-detector row CT scanner (Aquilion ONE™ / GENESIS Edition, Canon Medical Systems, Tokyo, Japan) was used. Scanning parameters were as follows: tube voltage, 120 kV; tube current, auto exposure control; tube rotation speed, 0.5 per second; slice thickness, 0.5 mm; reconstruction kernel, FC14; image reconstruction interval, 0.5 mm; helical pitch, 129 and interpolation method, 180 degrees interpolation method. Dynamic contrast-enhanced CT was performed using a bolus tracking technique, where a region of interest was placed on the abdominal aorta and the trigger threshold inside the region of interest was set at 120 HU. The first phase scan was started 8 s after the threshold was achieved following the administration of contrast material. The second phase image was obtained 15 s after the first arterial phase. The 3D images were reconstructed using Intuition™ Thin Client version 4.4.13.P7 software (TeraRecon, Tokyo, Japan).

Nakao T., Shimada M., Yoshikawa K., Tokunaga T., Nishi M., Kashihara H., Takasu C., Wada Y., Yoshimoto T., Yamashita S, & Iwakawa Y. (2022). Vascular variations encountered during laparoscopic surgery for transverse colon, splenic flexure, and descending colon cancer: a retrospective cohort study. BMC Surgery, 22, 170.

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Acromion Morphology Impact on ARCR

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The shoulders of patients of more than 25 years old (because the epiphyseal line of the acromion closes around 25 years) who underwent ALA along with ARCR at our institution between October 2019 and February 2021 were identified. Patients were diagnosed with RCT using 1.5- or 3.0-T MRI and the indication for ARCR was unmanageable pain or functional disability despite conservative treatment for more than 3 months. Preoperative CT examination was performed using Aquilion ONE / GENESIS Edition (Canon Medical Systems Corporation, Tochigi, Japan) for all patients indicated for ARCR. ALA was performed on shoulders with a CSA of >35° on the 3D model based on preoperative CT data. All patients who underwent performed ALA along with ARCR provided written informed consent before surgery. Shoulders with RCT that did not include supraspinatus tendon tear, shoulders that were not operated on according to the results of the 3D simulation, and shoulders with glenoid fracture including bony Bankart lesion were excluded from this study.

Oishi T., Kobayashi N., Yukizawa Y., Takagawa S., Honda H, & Inaba Y. (2022). Radiographs Are Comparable With 3-Dimensional Computed Tomography-Based Models as a Modality for the Preoperative Planning of the Arthroscopic Lateral Acromioplasty: A Retrospective Comparative Study. Arthroscopy, Sports Medicine, and Rehabilitation, 4(5), e1799-e1806.

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CT Imaging Protocol for Body Scans

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CT was performed using a 160- or 320-slice CT scanner (Aquilion Precision, Canon Medical Systems, Otawara, Japan, n = 34, or Aquilion ONE GENESIS Edition, Canon Medical Systems, n = 39). A pre-contrast scan was performed in all patients from the supraclavicular area to the symphysis pubis during a single breath hold. Tube current was adjusted individually using an auto-exposure control technique with a standard deviation setting of 15. The remaining scan parameters were as follows: tube voltage, 120 kVp; rotation time, 0.5 s; helical pitch, 0.83. Although post-contrast scans were also acquired in 31 patients, only the pre-contrast images were used in this study.
From the raw data of each patient, two sets of axial images were reconstructed, with a slice thickness/interval of 4/4 and 1/1 mm. A hybrid iterative reconstruction algorithm (AIDR 3D, Canon Medical Systems) with a weak strength setting was applied. The remaining reconstruction parameters were as follows: kernel, FC03; reconstruction field of view, 350 mm (pixel size, 0.68 × 0.68 mm).

Nakamoto A., Hori M., Onishi H., Ota T., Fukui H., Ogawa K., Masumoto J., Kudo A., Kitamura Y., Kido S, & Tomiyama N. (2022). Three-dimensional conditional generative adversarial network-based virtual thin-slice technique for the morphological evaluation of the spine. Scientific Reports, 12, 12176.

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Optimized Coronary CTA Protocol

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A 320-row CT was used to perform coronary CT angiography (Aquilion ONE Genesis Edition; Canon Medical Systems Corporation). Oral β-blocker (metoprolol, 20 or 40 mg) was used 1 h before the exam to achieve the target heart rate of 65 beats per minute. A maximum dose of 12.5 mg of landiolol (Corebeta; Ono Parmaceutical) was given intravenously if the heart rate was > 65 bpm at the CT room [18 ]. All patients received 0.6 mg of sublingual nitroglycerin (Nitropen; Nippon Kayaku) before imaging. Patients received 18.0 mg iodine/kg/s of iomeprol (Iomeron 350; Eisai) for 12 s, followed by a 30 ml saline flush. Images were reconstructed with slice thickness and increment of 0.50 mm and 0.25 mm, respectively, using a convolution kernel of FC04 with iterative reconstruction (AIDR 3D [adaptive iterative dose reduction using a three-dimensional processing algorithm]; Canon Medical Systems Corporation). Images were transferred to a workstation for postprocessing (Synapse Vincent, version 6.0; Fujifilm Medical).

Tomizawa N., Fujimoto S., Takahashi D., Nozaki Y., Fan R., Kudo A., Kawaguchi Y., Takamura K., Hiki M., Kadowaki S., Ikeda F., Kumamaru K.K., Watada H., Minamino T, & Aoki S. (2023). Energy loss is related to CT fractional flow reserve progression in type 2 diabetes mellitus patients. American Heart Hournal Plus: Cardiology Research and Practice, 35, 100328.

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Abdominal CT Imaging Protocol for Liver

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CT imaging was performed using an Aquilion ONE GENESIS Edition scanner (Canon Medical Systems Corporation, Otawara, Tochigi, Japan). An abdominal protocol was selected (liver, three phases, only portal phase used), with automatic exposure control on (so the system selects the mA depending on the phantom size and attenuation, SD10‐Quality 5 mm for FC18 and AIDR3De), 80 × 0.5 mm² collimation, 120 kV, 0.813 pitch, 0.5 s rotation time, 139 mA average and CTDI_vol = 4.4 mGy. Images were reconstructed with a FOV = 400.39 mm, 1 mm slice thickness and spacing (voxel size = 0.782 × 0.782 × 1 mm³), using Adaptive Iterative Dose Reduction Enhanced (AIDR3De STD) as the reconstruction method and FC08 reconstruction kernel.

Kalisvaart G.M., van Velden F.H., Hernández‐Girón I., Meijer K.M., Ghesquiere‐Dierickx L.M., Brink W.M., Webb A., de Geus‐Oei L., Slump C.H., Kuznetsov D.V., Schaart D.R, & Grootjans W. (2022). Design and evaluation of a modular multimodality imaging phantom to simulate heterogeneous uptake and enhancement patterns for radiomic quantification in hybrid imaging: A feasibility study. Medical Physics, 49(5), 3093-3106.

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Cardiac CT Imaging Protocol

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The CT system used was Aquilion ONE ViSION Edition™ or Aquilion ONE GENESIS Edition™ (320-ADCT, Canon Medical Systems Corporation, Otawara, Japan). The automatic contrast medium injector was Dual Shot (Nemoto Kyorindo Co., Ltd., Tokyo, Japan), the image analyzer was ZIOSTATION (M900, Ziosoft Inc., Tokyo, Japan), and the ECG monitor was Model 7800 (Chronos Medical Device Inc., Tokyo, Japan). As a pretreatment, metoprolol was orally administered at 20–40 mg on the day of the examination at a heart rate (HR) ≥61 bpm unless there was a contraindication (systolic blood pressure < 90 mmHg, severe atrioventricular block, heart failure). If the HR remained at ≥61 bpm even after the administration of metoprolol, it was controlled by an intravenous injection of landiolol at 12.5 mg.

Takamura K., Fujimoto S., Mita T., Kawaguchi Y.O., Kurita M., Kadowaki S., Kamo Y., Aoshima C., Nozaki Y.O., Takahashi D., Kudo A., Hiki M., Tomizawa N., Ikeda F., Satoh H., Watada H, & Minamino T. (2022). Identification of Risk Factors for Coronary Artery Disease in Asymptomatic Patients with Type 2 Diabetes Mellitus. Journal of Clinical Medicine, 11(5), 1226.

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