Atr alpha 2 spectrometer

Mechanochemical experiments were carried out in an in-house modified Makita (Jigsaw) ball mill that was equipped with reactors (diameter: 2.0 cm; height: 2.0 cm; volume of reactor: 13.2 mL). All reactors are stainless steel and equipped with stainless steel balls (diameter: 6 mm; mass: 0.90 g;). A FT-IR-Eco ATR Bruker Alpha II Spectrometer was used for the FT-IR analysis. The IR spectra were obtained by the attenuated total reflection (ATR) method. For each experiment, 16 scans were performed in the frequency range from 650 to 4000 cm⁻¹. Melting points of all the compounds were determined using a Koffler hot-stage apparatus and are uncorrected. NMR spectra were recorded on a Bruker Advance III 400 spectrometer using CDCl₃ or DMSO-d₆ as a solvent with tetramethyl silane used as internal standard. LC-MS/MS data were recorded on a Bruker Compact quadrupole time-of-flight (QToF) mass spectrometer. Raw mass spectrometry data were processed using MZmine software (version 2.38). Solvents and chemicals used were of analytical grade, which were purchased from Sigma Aldrich and used without further purification. The purity determination of the starting materials and reaction monitoring was performed by thin-layer chromatography (TLC) on Merck silica gel G F254plates.