Levofloxacin hydrate

Colchicine was purchased from Nacalai Tesque, Inc (Kyoto, Japan). Mitomycin C (MMC; 2-mg injection) was purchased from Kyowa Hakko Kirin Co., Ltd. (Tokyo, Japan). Ketamine hydrochloride (Ketalar for intramuscular injection; 500 mg) was purchased from Daiichi Sankyo Co., Ltd. (Tokyo, Japan). Xylazine hydrochloride (Selactar for injection; 2%) was purchased from Bayer Yakuhin Ltd. (Osaka, Japan). A 0.01% ophthalmic solution of betamethasone sodium phosphate was purchased from Shionogi Co., Ltd. (Osaka, Japan). A 0.5% ophthalmic solution of levofloxacin hydrate and a 0.4% ophthalmic solution of oxybuprocaine were supplied by Santen Pharmaceutical Co., Ltd. (Osaka, Japan).

Preoperative medication 0.5% levofloxacin hydrate (Cravit®, Santen, Osaka, Japan) every 6 h and 0.1% bromfenac sodium hydrate (Bronuck®, Taejoon Pharm., Seoul, Korea) every 12 h were used for 3 days before surgery. At the day of surgery, 0.5% Moxifloxacin (Vigamox®, Alcon) every 2 h, 0.1% fluorometholone (Flucon®, Alcon) every 6 h, and 0.1% bromfenac sodium hydrate (Bronuck®) every 12 h were used. At the day after surgery, 0.5% Moxifloxacin was used every 6 h, along with the other eye drops used on 1 day for the next 1 month.