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Dpp4 inibitor

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DPP4-inibitor is a type of laboratory equipment used for the inhibition of the enzyme dipeptidyl peptidase-4 (DPP4). This enzyme plays a role in the regulation of various physiological processes. The DPP4-inibitor is designed to facilitate the study and analysis of DPP4 activity and its effects in a controlled laboratory setting.

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Lab products found in correlation

Halt protease inhibitor, by Thermo Fisher Scientific (2 mentions) Contour glucometer, by Bayer (2 mentions)

2 protocols using dpp4 inibitor

1

Glucose Homeostasis in GKO-NSG Mice

Check if the same lab product or an alternative is used in the 5 most similar protocols
After a 5-hour fast (starting from 9–10 AM), mice were
administered an intraperitoneal (IP) injection of D-glucose (3 g/kg body
weight). Blood glucose levels were measured with a Contour glucometer (Bayer) at
0, 5, 15, 30, 45, 60, 90, and 120 minutes post injection and EDTA-treated plasma
samples were collected for insulin hormone assays at the same time intervals.
5–7 month-old male GKO-NSG, GKO-NSG Tx, and
NSG littermate control mice were used. For circulating
GLP-1 assessment, mice were fasted for 6 hours (starting at 9AM), then D-glucose
(6 g/ kg body weight) was given by oral gavage. Blood glucose was measured with
a Contour glucometer (Bayer) at 0, 5, 15, 30, 60, 90, 120, and 180 minutes
post-gavage and EDTA-, DPP4-inibitor- (Millipore), and HALT protease inhibitor-
(Thermo Scientific) treated plasma samples were collected at 0, 15, and 30
minutes post-gavage. 2.5–3 month-old male and female
GKO-NSG and NSG littermate control mice
were used.
Tellez K., Hang Y., Gu X., Chang C.A., Stein R.W, & Kim S.K. (2020). In vivo studies of glucagon secretion by human islets transplanted in mice. Nature metabolism, 2(6), 547-557.
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2

Glucose Homeostasis in GKO-NSG Mice

Check if the same lab product or an alternative is used in the 5 most similar protocols
After a 5-hour fast (starting from 9–10 AM), mice were
administered an intraperitoneal (IP) injection of D-glucose (3 g/kg body
weight). Blood glucose levels were measured with a Contour glucometer (Bayer) at
0, 5, 15, 30, 45, 60, 90, and 120 minutes post injection and EDTA-treated plasma
samples were collected for insulin hormone assays at the same time intervals.
5–7 month-old male GKO-NSG, GKO-NSG Tx, and
NSG littermate control mice were used. For circulating
GLP-1 assessment, mice were fasted for 6 hours (starting at 9AM), then D-glucose
(6 g/ kg body weight) was given by oral gavage. Blood glucose was measured with
a Contour glucometer (Bayer) at 0, 5, 15, 30, 60, 90, 120, and 180 minutes
post-gavage and EDTA-, DPP4-inibitor- (Millipore), and HALT protease inhibitor-
(Thermo Scientific) treated plasma samples were collected at 0, 15, and 30
minutes post-gavage. 2.5–3 month-old male and female
GKO-NSG and NSG littermate control mice
were used.
Tellez K., Hang Y., Gu X., Chang C.A., Stein R.W, & Kim S.K. (2020). In vivo studies of glucagon secretion by human islets transplanted in mice. Nature metabolism, 2(6), 547-557.
+ Open protocol
+ Expand

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