Optometry system

Manufactured by Cerebral Mechanics

Sourced in Canada

The OptoMetry system is a laboratory equipment product designed for optical measurements. It provides precise data acquisition and analysis capabilities for various optical applications. The core function of the OptoMetry system is to enable accurate and reliable optical measurements, without interpreting or extrapolating its intended use.

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Lab products found in correlation

Close spelling variants of this product

OptoMetry (3 citations) Virtual Optometry System (3 citations)

2 protocols using optometry system

Visual Acuity Assessment using Optokinetic Reflex

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Visual acuity was evaluated using the OptoMetry system (Cerebral Mechanics, Lethbridg, AB, Canada). To evaluate the visual acuity, 6 different spatial frequencies were used as follows: 0.031, 0.061, 0.092, 0.103, 0.194, and 0.272 cycles/degree (cyc/deg) at 100% of contrast sensitivity. For each frequency, a set of 20 random tests (10 clockwise and 10 counterclockwise) were performed per animal. When the stripes of the cylinder started rotating (12 degrees/s), the mouse moved the head in the same direction of stripe rotation (optokinetic reflex). The head movements of each animal were visualized through a video camera coupled to the software of the equipment. A red star cursor in the video frame indicated the head of the animal. This cursor allowed us to visualize the movements and served to fix the center of the virtual cylinder at a constant distance. The number of optokinetic reflexes elicited in the mice was registered.

Valdés-Sánchez L., Borrego-González S., Montero-Sánchez A., Massalini S., de la Cerda B., Díaz-Cuenca A, & Díaz-Corrales F.J. (2022). Mesoporous Silica-Based Nanoparticles as Non-Viral Gene Delivery Platform for Treating Retinitis Pigmentosa. Journal of Clinical Medicine, 11(8), 2170.

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Measuring Visual Acuity in Mice

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Visual acuity was measured using an Optometry System (CerebralMechanics Inc., Lethbridge, Alberta, Canada), as previously described^{36 (link)}. After disinfecting the platform to remove a prior mouse’s scent, mice were placed on the platform for 5 minutes to habituate. An observer assessed for reflexive head-tracking movements that correlated with the frequency of the virtual sine wave grating on the monitors using 100% contrast in normal lighting conditions. The visual acuity threshold was determined at the highest spatial frequency (cycle/degree) when the animal stopped tracking. Right and left eyes were tested separately and averaged together to get one spatial frequency per animal. Analyses was performed in young (3 month old, n=4–5 mice per genotype) and old (17 month old) mice (n=5 mice per genotype).

Berger A., Rosenthal D, & Spiegel S. (1995). Sphingosylphosphocholine, a signaling molecule which accumulates in Niemann-Pick disease type A, stimulates DNA-binding activity of the transcription activator protein AP-1.. Proceedings of the National Academy of Sciences of the United States of America, 92(13), 5885-5889.

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