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P stat3 p y705

Manufactured by Cell Signaling Technology
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P-STAT3(p-Y705) is a lab equipment product that detects the phosphorylated form of STAT3 at tyrosine 705. It is used to measure the activation of the STAT3 signaling pathway.

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Lab products found in correlation

Ripa buffer, by Santa Cruz Biotechnology (1 mentions) Cleaved caspase 3, by Cell Signaling Technology (1 mentions) P erk, by Cell Signaling Technology (1 mentions) Stat3, by Cell Signaling Technology (1 mentions) Gapdh, by Cell Signaling Technology (1 mentions) Bcl 2, by Cell Signaling Technology (1 mentions) β catenin, by Cell Signaling Technology (1 mentions) P mtor, by Cell Signaling Technology (1 mentions) P β catenin, by Cell Signaling Technology (1 mentions) Everolimus, by LC Laboratories (1 mentions)

Spelling variants of this product

STAT3 (1075 citations) P-STAT3 (935 citations) P-STAT3 (Y705) (111 citations) P-STAT3 (Y705) antibody (6 citations) Anti-p-STAT3 (Y705) antibody (4 citations) P-STAT3 Y705 (9145 (2 citations)

2 protocols using p stat3 p y705

1

STAT3 Immunoblotting Protocol

Cited 1 time
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Cells were harvested, lysed in RIPA buffer (Santa Cruz Biotechnology; Santa Cruz, CA), and protein was quantified and electrophoresed as previously described (7 (link)). Immunoblotting was performed using the following antibodies: total STAT3, and p-STAT3(p-Y705) (Cell Signaling; Danvers, MA) at a 1:1000 dilution.
Arpin C.C., Mac S., Jiang Y., Cheng H., Grimard M., Page B.D., Kamocka M.M., Haftchenary S., Su H., Ball D., Rosa D.A., Lai P.S., Gómez-Biagi R.F., Ali A.M., Rana R., Hanenberg H., Kerman K., McElyea K.C., Sandusky G.E., Gunning P.T, & Fishel M.L. (2016). Applying Small Molecule Signal Transducer and Activator of Trancription-3 (STAT3) Protein Inhibitors as Pancreatic Cancer Therapeutics. Molecular cancer therapeutics, 15(5), 794-805.
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2

Sorafenib and Everolimus Combination Therapy

Cited 1 time
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Sorafenib tysolate and everolimus were purchased form L.C. Laboratories (Woburn, MA). For all in vivo studies, sorafenib and everolimus were prepared as previously described [9 (link),30 (link)]. Antibodies for western blot and immunohistochemical analysis were purchased as follows: β-catenin (#8480), Bcl-2 (#2870), BIM (#2933), cleaved caspase-3 (#9661), ERK (#9102), GAPDH (#2118), mTOR (#2983), p-β-catenin (#9561), p-ERK (#4370), p-mTOR (#2971), p-S6 (#2211), p-STAT3-pY705 (#9145), p-STAT3-pY727 (#9134), S6 (#2217) and STAT3 (#4904) antibodies from Cell Signaling Technology (Danvers, MA); AR (#RB-9030), PCNA (#RB-9055) and Ki67 (#RB-9043) antibodies from Thermo Scientific (Waltham, MA); cyclin B1 (sc-752), cyclin D1 (sc-753) antibodies from Santa Cruz Biotechnology (Dallas, TX); CD31 (#550300) from BD Biosciences (San Jose, CA).
Yamamoto Y., De Velasco M.A., Kura Y., Nozawa M., Hatanaka Y., Oki T., Ozeki T., Shimizu N., Minami T., Yoshimura K., Yoshikawa K., Nishio K, & Uemura H. (2015). Evaluation of in vivo responses of sorafenib therapy in a preclinical mouse model of PTEN-deficient of prostate cancer. Journal of Translational Medicine, 13, 150.
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