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Oksm lentivirus reprogramming kit

Manufactured by Merck Group
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The OKSM Lentivirus reprogramming kit is a laboratory tool used for the generation of induced pluripotent stem cells (iPSCs) from various cell types. The kit contains lentiviral particles expressing the reprogramming factors Oct4, Sox2, Klf4, and c-Myc, which are necessary for the conversion of differentiated cells into a pluripotent state. The kit provides a convenient and standardized method for researchers to establish iPSC lines for their studies.

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Lab products found in correlation

Human stemcca cre excisable, by Merck Group (2 mentions)

Spelling variants of this product

Lentivirus (36 citations) Human STEMCCA Cre-Excisable Constitutive Polycistronic (OKSM) Lentivirus Reprogramming Kit (3 citations)

2 protocols using oksm lentivirus reprogramming kit

1

Reprogramming of AD-HIES Fibroblasts to iPSCs

Cited 1 time
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Fibroblasts from AD-HIES patients were reprogrammed with the Human STEMCCA Cre-Excisable Constitutive Polycistronic (OKSM) Lentivirus reprogramming kit (Millipore). iPSC colonies were collected 21 days post-transduction, maintained in full E8 medium at 37°C with 5% CO2 and passaged with 0.5mM EDTA every 3–5 days (Jin et al., 2016 (link)).
Jin H., Yu Z., Navarengom K., Liu Y., Dmitrieva N., Hsu A.P., Schwartzbeck R., Cudrici C., Ferrante E.A., Yang D., Holland S.M., Freeman A.F., Boehm M, & Chen G. (2019). Generation of human induced pluripotent stem cell lines (NIHTVBi011-A, NIHTVBi012-A, NIHTVBi013-A) from autosomal dominant Hyper IgE syndrome (AD-HIES) patients carrying STAT3 mutation. Stem cell research, 41, 101586.
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2

Reprogramming of AD-HIES Fibroblasts to iPSCs

Cited 1 time
Check if the same lab product or an alternative is used in the 5 most similar protocols
Fibroblasts from AD-HIES patients were reprogrammed with the Human STEMCCA Cre-Excisable Constitutive Polycistronic (OKSM) Lentivirus reprogramming kit (Millipore). iPSC colonies were collected 21 days post-transduction, maintained in full E8 medium at 37°C with 5% CO2 and passaged with 0.5mM EDTA every 3–5 days (Jin et al., 2016 (link)).
Jin H., Yu Z., Navarengom K., Liu Y., Dmitrieva N., Hsu A.P., Schwartzbeck R., Cudrici C., Ferrante E.A., Yang D., Holland S.M., Freeman A.F., Boehm M, & Chen G. (2019). Generation of human induced pluripotent stem cell lines (NIHTVBi011-A, NIHTVBi012-A, NIHTVBi013-A) from autosomal dominant Hyper IgE syndrome (AD-HIES) patients carrying STAT3 mutation. Stem cell research, 41, 101586.
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