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Optima ct580

Manufactured by GE Healthcare
Sourced in United States

The Optima CT580 is a computed tomography (CT) scanner developed by GE Healthcare. It is designed to capture high-quality medical images for diagnostic purposes. The Optima CT580 utilizes advanced imaging technology to provide detailed visualizations of the body's internal structures.

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8 protocols using optima ct580

1

Validation of Bowtie Profile Measurements

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For the purpose of independent validation of the measured bowtie profiles, HVL profiles data from a GE Optima CT580 scanner (from the study by Randazzo and Tambasco11 (link)) were generously provided by the authors. As from GE’s technical reference manual, the Optima CT580 share the same x-ray tube and bowtie profiles with the Discovery CT 590 RT scanner therefore those data can be compared with the results calculated from this study from a CT590 RT scanner. The HVL profiles were calculated using the Spektr function “SpektrHVLn”, with only a small modification of the HVL accuracy, from 0.001 mm to 0.0001 mm.
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2

CT Phantom Scanning Optimization

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Using, tube voltage of 120 kV and tube current 200 mA and 400 mA on two different CT scanners (Optima CT580 and Discovery CT590 RT), both from GE Medical Systems (Chicago, Illinois, United States). Scans of four different setup arrangements, produced by shifting the boxes inside the phantom, were acquired (16 CT scans in total). Different CT slice thicknesses were acquired (0.625 mm, 1.25 mm, 2.5 mm).
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3

Radiotherapy Imaging with Optima CT 580

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The Optima CT 580 RT scanner from General Electric Healthcare-USA was employed to acquire patient images. This 80cm big bore CT scanner is designed explicitly for radiotherapy and includes a flat RT couch. The Optima 580 is a 16-slice scanner, meaning it captures 16 slices in a single rotation of its gantry and offers various slice thickness options, ranging from 0.625mm to 10mm. Moreover, this scanner can acquire 4D-CT images, accommodating helical and axial scanning techniques (Figure 1).
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4

4D-CT and 4D-MRI Imaging Protocol

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All patients underwent CT and MRI imaging studies under a prospective protocol approved by the institutional review board (IRB). The time interval between CT and MRI studies was less than 1 week. Patients were in a head-first supine position with arms up. CT scans were performed on a 16-slice scanner (Optima CT580; GE Healthcare, Milwaukee, WI) equipped with the Real-time Position Management (RPM) system (Varian Medical Systems, Palo Alto, CA) and AdvantageSim 4D software (GE Healthcare, Milwaukee, WI). 4D-CT scans were performed in cine mode with the following parameters: 120 kV, variable mA, gantry rotation period of 1 second, and slice thickness of 2.5mm. The cine duration time was set to be the patient’s breathing period plus 1.5 seconds.
MRI scans were performed on a 3.0 Tesla system (MAGNETOM Verio, Siemens Healthcare, Germany) equipped with a 6-channel body matrix coil. No special immobilization was used. The imaging protocol included an 8-minute free-breathing SG-KS-4D-MRI scan (prescribed isotropic spatial resolution = 1.56 mm, a cubic imaging volume of 300×300×300 mm3, flip angle=10°, TR/echo time (TE)=5.8/2.6ms, readout band width=399Hz/pixel) and two 1.2 minute free-breathing cine 2D-MRI spoiled gradient recalled echo (GRE) scans with orthogonal imaging planes traversing the tumor (351 ms/frame, 1.56-mm in-plane spatial resolution, 8-mm slice thickness).
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5

CT Scan for Treatment Planning

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A Computed Tomography (CT) scan, with a large-bore CT scanner (GE Healthcare, Optima CT 580, USA), was performed for treatment planning. Patients were placed in the supine position, with arms above their heads, using the ORFIT board system (Orfit Industries, Wijnegem, Belgium). An ORFIT thermoplastic mask was used to reduce set-up positioning errors.
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6

Retrospective COVID-19 CT Imaging Study

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This retrospective study was approved by the ethics committees of the participating centers. Written consent was waived with approval. We included 1141 volumetric chest CT exams from 9 medical centers, among which 312 volumetric CT images were from PCR-positive COVID-19 patients. COVID-19 patients were collected from three centers and various scanner models, including Emotion 16 (Siemens Healthcare), NeuViz Dual (Neusoft Medical Systems), and Optima CT580 (GE Healthcare). All CT images were acquired in each center using the same protocol and were reconstructed using a filtered backprojection (FBP) algorithm (Table 1).

Acquisition parameters of full-dose and low-dose chest CT protocols

ParametersFull-dose CTLow-dose CT
CTDIvol (mGy)6.5 (4.16–10.5)0.72 (0.66–1.03)
Voltage (kVp)100–12090
Tube current (mA)100–15020–45
Pitch factor1.3–1.80.75
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7

Breast Cancer Radiotherapy with DIBH Technique

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A general hospital-based informed consent was obtained for all patients.
Sixteen patients receiving radiation therapy for localized carcinoma of the right breast were included retrospectively (radiation to loco-regional lymphatic regions was excluded). The median age was 60 years (range, 39–83 years; mean: 59 years). All patients were treated using the DIBH technique.
For the planning computer tomography (CT), each patient was immobilised on an indexed board with the arms placed above the head. Patients unable to hold their breath for a minimum of 20 s were excluded from the DIBH technique and study. Breathing was tracked using the Real-time Position ManagementTM (RPM) system (Varian Medical Systems, Palo Alto, CA) with patients receiving live, visual feedback.
Two CT scans were acquired for each patient on a GE Optima CT580 wide bore CT scanner with a slice separation of 2.5 mm. One scan was done in free-breathing (FB) and one in DIBH. Both scans were acquired with the same length and same position, from the bottom of the chin to approximately the level of L3-spinebody. The Eclipse™ (Varian) planning system was used for volume delineation and treatment planning.
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8

Breast Cancer Surgery CT Imaging Protocol

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All patients underwent two sets of planning CT scans pre- and postoperatively in the treatment position, with a slice thickness of 2.5 mm. Patients were scanned with an Optima CT580 CT scanner (GE Healthcare, Buckinghamshire, UK), which had an 80 cm gantry opening and indexed table (Civco indexed carbon fiber MT-IL4101; Civco Medical Solutions, Kalona, IA, USA), specific for RT. Prior to CT scanning, the margins of palpable glandular breast tissue were marked with a thin CT-compatible Radio Opac wire by the radiation oncologist. Patients were immobilized in the supine treatment position; their shoulders and arms were fixed using a breast board (C-Qual breast inclined plane; Civco Medical Solutions) with knee support. The breast board index parameters were recorded in the patients' chart for the purpose of using the identical parameters in postoperative CT. All CT images were imported to a treatment planning system (Eclipse version 8.1; Varian Medical Systems, Palo Alto, CA, USA). Both CTs were fused using rigid registration on a user-defined region of interest, superposing the sternum and ipsilateral chest wall. During the fusion process, the nipple, skin and parenchymal breast tissue were not assigned priority due to the change in breast configuration following OP-BCS.
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