Verio 3 tesla mri system

The imaging protocol, QSM reconstruction and spatial normalisation methods (briefly summarised below) are essentially identical to those in a previous ageing study (Acosta‐Cabronero et al., 2016).
All participants were scanned on a Siemens Verio 3 Tesla MRI system with a 32‐channel head coil (Siemens Medical Systems, Erlangen, Germany) under the following imaging protocol:
T₁‐weighed data were acquired using a 3D MPRAGE sequence (Mugler & Brookeman, 1990) with the following scan parameters: Inversion time = 1,100 ms, flip angle (α) = 7°, echo time (TE) = 4.37 ms, receiver bandwidth (RB) = 140 Hz per pixel, echo spacing = 11.1 ms, repetition time (TR) = 2,500 ms; 256 × 256 × 192 matrix dimensions (straight‐sagittal orientation), 1 × 1 × 1 mm³ voxel size, twofold parallel acceleration and further 7/8 partial Fourier undersampling for phase encoding. The total scan time was 5:08 min.
T2*‐/susceptibility‐weighted data were obtained from a fully flow‐compensated, 3D spoiled gradient‐echo sequence. Scan parameters were: α = 17^°, TE = 20 ms, RB = 100 Hz per pixel, TR = 28 ms; matrix, 256 × 224 × 80 with voxel resolution of 1 × 1 × 2 mm³; and twofold parallel acceleration for phase encoding. The total scan time was 5:32 min. All susceptibility maps were inspected to exclude subjects with severe calcifications or microbleeds.