Ms excel

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MS Excel is a spreadsheet software application developed by Microsoft. It provides a grid-based interface for organizing, analyzing, and visualizing data. MS Excel's core function is to enable users to perform calculations, create charts and graphs, and automate various data-related tasks.

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Lab products found in correlation

Imagej, by OriginLab (11 mentions) Origin 2016, by OriginLab (11 mentions) Prism 7, by GraphPad (10 mentions) Originpro 8, by OriginLab (2 mentions) Originpro 2020, by OriginLab (2 mentions) Originpro 2016, by OriginLab (1 mentions) Origin version 2021, by OriginLab (1 mentions) Prism 8, by GraphPad (1 mentions) Icp ms, by Agilent Technologies (1 mentions) 0.45 μm membrane, by Cytiva (1 mentions) 50 ml plastic centrifuge tubes, by Corning (1 mentions)

18 protocols using ms excel

Synergistic Effects of BOZ and ALA

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Evaluation of the results was performed by using the MS Excel and OriginPro 8.0 (OriginLab Corporation, Northampton, MA, USA) software. The data were statistically analyzed by the use of one-way analysis of variance (ANOVA) followed by Fishers Least Significant Difference (Fishers LSD) post hoc test. Every treated sample was compared to the matching untreated, medium control. The result of this analysis is found directly above the columns. If there is any statistical difference between the means of the group members, the level of significance is presented on a horizontal line connecting the two significantly different data. The image quantification was performed by ImageJ software. The relative protein levels were determined by Image Lab software. The levels of significance are shown as follows: x: P < 0.05; y: P < 0.01; z: P < 0.001. The combined effects of different concentrations of BOZ with ALA were determined, and the combination index (CI) values were evaluated using CompuSyn software. Combination index < 1, = 1, or > 1 represents synergism, additive effect or antagonism, respectively.

Takács A., Lajkó E., Láng O., Istenes I, & Kőhidai L. (2020). Alpha-lipoic acid alters the antitumor effect of bortezomib in melanoma cells in vitro. Scientific Reports, 10, 14287.

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Statistical Analysis of Experimental Data

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The experiments conducted in this investigation were analyzed using statistical tools such as MS Excel and Origin software (OriginPro 2016, Origin Lab Corporation, Northampton, MA, USA). All the values represented in the graphs were mean with standard deviation. The ANOVA significance were depicted in different letters on the respective groups and experiments; the statistical significance was determined using Tukey HSD (honestly significant difference) test.

Mani V.M., Soundari A.J., Balasubramanian B., Park S., Issara U., Preethi K, & Liu W.C. (2021). Evaluation of Dimer of Epicatechin from an Endophytic Fungus Curvularia australiensis FC2AP on Acute Toxicity Levels, Anti-Inflammatory and Anti-Cervical Cancer Activity in Animal Models. Molecules, 26(3), 654.

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Cellular Signaling Pathway Analysis

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All presented data were obtained from at least three cell cultures. All values are given as the mean ± standard error (SEM) or as individual cellular signals in experiments. Statistical analyses were performed by paired t-test. Differences are significant * p < 0.05, ** p < 0.01, and *** p < 0.001. n/s—data not significant (p > 0.05). MS Excel, ImageJ, Origin 2016 (OriginLab, Northampton, MA, USA), and Prism GraphPad 7 (GraphPad Software, RRID: SCR_002798) software was used for data and statistical analysis.

Varlamova E.G., Plotnikov E.Y., Baimler I.V., Gudkov S.V, & Turovsky E.A. (2023). Pilot Study of Cytoprotective Mechanisms of Selenium Nanorods (SeNrs) under Ischemia-like Conditions on Cortical Astrocytes. International Journal of Molecular Sciences, 24(15), 12217.

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Immunofluorescence Staining of Cells

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All presented data were obtained from at least three cell cultures from 2–3 different passages. All values are given as mean ± standard error (SEM) or as individual cellular signals in experiments. Statistical analyses were performed by paired t-test. Differences are significant * p < 0.05, ** p < 0.01, and *** p < 0.001. n/s—data not significant (p > 0.05). MS Excel, ImageJ, Origin 2016 (OriginLab, Northampton, MA, USA), and Prism GraphPad 7 (GraphPad Software, RRID: SCR_002798) software was used for data and statistical analysis.

Varlamova E.G., Plotnikov E.Y, & Turovsky E.A. (2022). Neuronal Calcium Sensor-1 Protects Cortical Neurons from Hyperexcitation and Ca2+ Overload during Ischemia by Protecting the Population of GABAergic Neurons. International Journal of Molecular Sciences, 23(24), 15675.

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Selenium Nanoparticles for Cell Viability

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All presented data were obtained from at least three cell cultures from 3 different passages. All values are given as mean ± standard error (SEM). PCR analysis was performed and analyzed as blinded, the experimenter was unaware of the concentrations of SeNPs. Experiments using fluorescence microscopy were performed with a significant number of replicates and their statistical processing provides significant differences between the experimental groups. Statistical analyses were performed by one-way ANOVA followed by the Tukey–Kramer test. MS Excel, ImageJ, Origin 2016 (OriginLab, Northampton, MA, USA), and Prism GraphPad 7 (GraphPad Software, RRID: SCR_002798) software was used for data and statistical analysis^{40 (link)}.

Turovsky E.A., Mal’tseva V.N., Sarimov R.M., Simakin A.V., Gudkov S.V, & Plotnikov E.Y. (2022). Features of the cytoprotective effect of selenium nanoparticles on primary cortical neurons and astrocytes during oxygen–glucose deprivation and reoxygenation. Scientific Reports, 12, 1710.

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Statistical Analysis of Experimental Data

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The drawings and statistical analysis were performed using MS Excel and Origin version 2021 (Origin Lab., Hampton, VA, USA). All data are presented as the arithmetic mean ± standard deviation. For the calculation of the statistical significance, two-sample t-tests (two-tailed) were performed (alpha level 0.05). An analysis of variance was performed to test for equal variances prior to t-test analysis.

Dold J., Kehr C., Hollmann C, & Langowski H.C. (2022). Non-Destructive Measuring Systems for the Evaluation of High Oxygen Stored Poultry: Development of Headspace Gas Composition, Sensory and Microbiological Spoilage. Foods, 11(4), 592.

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Intracellular Calcium Signaling in Cells

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All presented data were obtained from at least three cell cultures from 2–3 different passages. All values are given as mean ± standard error (SEM). Statistical analyses were performed by Two-way ANOVA, followed by Sidak’s multiple comparison test or by paired t-test. Differences are significant * p < 0.05, ** p < 0.01, and *** p < 0.001. n/s—data not significant (p > 0.05). MS Excel, ImageJ, Origin 2016 (OriginLab, Northampton, MA, USA), and Prism GraphPad 7 (GraphPad Software, RRID: SCR_002798) software was used for data and statistical analysis.

Turovsky E.A., Varlamova E.G, & Plotnikov E.Y. (2021). Mechanisms Underlying the Protective Effect of the Peroxiredoxin-6 Are Mediated via the Protection of Astrocytes during Ischemia/Reoxygenation. International Journal of Molecular Sciences, 22(16), 8805.

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Neuronal Cell Culture Analysis

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All presented data were obtained from at least three cell cultures from 2–3 different passages. All values are given as mean ± standard error (SEM). Statistical analyses were performed by two-way ANOVA, followed by Sidak’s multiple comparison test or by paired t-test. MS Excel, ImageJ, Origin 2016 (OriginLab, Northampton, MA, USA), and Prism GraphPad 7 (GraphPad Software, RRID: SCR_002798) software were used for data and statistical analysis. In our experiments, we did not perform a predetermined sample size calculation to assess the effects. N—number of neurons that were analyzed in an experiment; n—number of the experiments.

Turovsky E.A., Turovskaya M.V., Fedotova E.I., Babaev A.A., Tarabykin V.S, & Varlamova E.G. (2021). Role of Satb1 and Satb2 Transcription Factors in the Glutamate Receptors Expression and Ca2+ Signaling in the Cortical Neurons In Vitro. International Journal of Molecular Sciences, 22(11), 5968.

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Cellular Signaling Assay Protocol

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All presented data were obtained from at least three cell cultures from two to three different passages. All values are given as mean ± standard error (SEM) or as individual cellular signals in experiments. Statistical analyses were performed by paired t-test. Differences are significant at * p < 0.05, ** p < 0.01, and *** p < 0.001. n/s—data not significant (p > 0.05). MS Excel, ImageJ, Origin 2016 (OriginLab, Northampton, MA, USA), and Prism GraphPad 7 (GraphPad Software, RRID: SCR_002798) software were used for data and statistical analysis.

Varlamova E.G., Khabatova V.V., Gudkov S.V., Plotnikov E.Y, & Turovsky E.A. (2022). Cytoprotective Properties of a New Nanocomplex of Selenium with Taxifolin in the Cells of the Cerebral Cortex Exposed to Ischemia/Reoxygenation. Pharmaceutics, 14(11), 2477.

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Cellular Signaling Pathways Analysis

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All presented data were obtained from at least three cell cultures from 2 to 3 different passages. All values are given as mean ± standard error (SEM) or as individual cellular signals in experiments. Statistical analyses were performed by paired t-test. Differences are significant * p < 0.05, ** p < 0.01, and *** p < 0.001. n/s—data not significant (p > 0.05). MS Excel, ImageJ, Origin 2016 (OriginLab, Northampton, MA, USA), and Prism GraphPad 7 (GraphPad Software, RRID: SCR_002798) software were used for data and statistical analysis.

Varlamova E.G., Turovsky E.A., Babenko V.A, & Plotnikov E.Y. (2021). The Mechanisms Underlying the Protective Action of Selenium Nanoparticles against Ischemia/Reoxygenation Are Mediated by the Activation of the Ca2+ Signaling System of Astrocytes and Reactive Astrogliosis. International Journal of Molecular Sciences, 22(23), 12825.

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