Axio scan z1 brightfield fluorescence slide scanner

Manufactured by Zeiss

The Axio Scan Z1 Brightfield/Fluorescence Slide Scanner is a digital slide scanner designed for high-throughput imaging of histological samples. It is capable of capturing both brightfield and fluorescence images from microscope slides. The core function of the Axio Scan Z1 is to digitize and archive microscopic specimens for analysis and collaboration.

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Lab products found in correlation

Formalin, by Thermo Fisher Scientific (1 mentions) Halo software, by Indica Labs (1 mentions) Hematoxylin and eosin, by Thermo Fisher Scientific (1 mentions) Buffered formalin, by Thermo Fisher Scientific (1 mentions) Zen blue 3, by Zeiss (1 mentions)

Close spelling variants of this product

Axio Scan.Z1 slide scanner Axio Scan.Z1 slide Axio Scan.Z1 scanner Slide Scanner Axio Scan Axio Scan.Z1 Axio Scanner Z1 Axio slide scanner Slide scanner

2 protocols using axio scan z1 brightfield fluorescence slide scanner

Tissue Preparation and T-Cell Analysis

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Tissues were fixed in 10% formalin overnight (Fisher Scientific), incubated in graded ethanol, embedded in paraffin, and cut into 5-μm-thick sections. These Sects. (5-μm-thick) were air-dried and fixed in 4% paraformaldehyde (PFA) (Ted Pella Inc.). For CD8 + and CD4 + T cell analysis, tissues were stained using Bond RXm autostainer (Leica Biosystems). For all quantifications, whole tissue slide scans were obtained at 10 × magnification on Zeiss Axio Scan Z1 Brightfield/Fluorescence Slide Scanner. Whole tissue slide scans at 10 × magnification were analyzed with HALO software (Indica Labs).

Panni U.Y., Chen M.Y., Zhang F., Cullinan D.R., Li L., James C.A., Zhang X., Rogers S., Alarcon A., Baer J.M., Zhang D., Gao F., Miller C.A., Gong Q., Lim K.H., DeNardo D.G., Goedegebuure S.P., Gillanders W.E, & Hawkins W.G. (2023). Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology. Cancer Immunology, Immunotherapy, 72(8), 2813-2827.

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Histological Analysis of Brain Tissues

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Brain tissues were fixed in 10% buffered formalin (Thermo Fisher Scientific), embedded in paraffin, cut into 5 μm thick sections, and stained with hematoxylin and eosin (Thermo Fisher Scientific). Whole-tissue scans at 20× original magnification were obtained on a Zeiss Axio Scan Z1 bright-field/fluorescence Slide Scanner, and images were postprocessed using the Zeiss Zen Blue 3.1 software.

Nair S., Mazzoccoli L., Jash A., Govero J., Bais S.S., Hu T., Fontes-Garfias C.R., Shan C., Okada H., Shresta S., Rich J.N., Shi P.Y., Diamond M.S, & Chheda M.G. (2021). Zika virus oncolytic activity requires CD8+ T cells and is boosted by immune checkpoint blockade. JCI Insight, 6(1), e144619.

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