Kt 182

Manufactured by Cayman Chemical

Sourced in United States

KT-182 is a laboratory instrument designed for the analysis and purification of chemical compounds. It features a high-performance liquid chromatography (HPLC) system with a variable wavelength detector. The core function of KT-182 is to separate, identify, and quantify various chemical substances within a sample.

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Lab products found in correlation

3 protocols using kt 182

Pharmacological Agents for Animal Studies

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Ketamine/xylazine was purchased from Sigma-Aldrich (St. Louis, MO) and isoflurane from VetOne. (IL, USA). MJN110, KT-182, SR141716 (Rimonabant), and SR144528 were purchased from Cayman Chemicals (Ann Arbor, MI). All other chemicals, unless noted were purchased from Sigma-Aldrich (St. Louis, MO).

Liktor-Busa E., Levine A.A., Palomino S.M., Singh S., Wahl J., Vanderah T.W., Stella N, & Largent-Milnes T.M. (2023). ABHD6 and MAGL control 2-AG levels in the PAG and allodynia in a CSD-induced periorbital model of headache. Frontiers in Pain Research, 4, 1171188.

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Analytical Reagents for Biochemical Assays

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AG, KT‐182, N‐oleylethanolamine‐d₂ (OEA‐d₂) and WWL70 were supplied by Cayman Chemicals (Ann Arbor, MI, USA) and 4‐MUH, 4‐MU, ACEA, butylated hydroxytoluene and zardaverine by Sigma‐Aldrich (Madrid, Spain). TOFA was supplied by Abcam (Cambridge, UK).

Miralpeix C., Reguera A.C., Fosch A., Casas M., Lillo J., Navarro G., Franco R., Casas J., Alexander S.P., Casals N, & Rodríguez‐Rodríguez R. (2021). Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status. British Journal of Pharmacology, 178(7), 1507-1523.

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Profiling Endocannabinoid Metabolism Modulators

Cited 3 times

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2-AG, anandamide (AEA), PGE₂-G, PGE₂, and their deuterated analogs 2-AG-d5, AEA-d8, PGE₂-G-d5, and PGE₂-d4 were purchased from Cayman Chemical; stock solutions were prepared in ethanol (10 mg/mL). JZL184, a selective inhibitor of monoacylglyerol lipase, and KT182, an inhibitor of ABHD6,^{31 (link)} were purchased from Cayman Chemical. KT109, an inhibitor of DAGLβ,^{29 (link),30 (link)} and KT195, an inhibitor of serine hydrolase ABHD6,^{29 (link),30 (link)} were purchased from Sigma-Aldrich. Stock solutions of enzyme inhibitors were prepared in dimethyl sulfoxide (DMSO, 10 mg/mL) and diluted to their final concentration in sterile saline with Tween 80.

Khasabova I.A., Gable J., Johns M., Khasabov S.G., Kalyuzhny A.E., Golovko M.Y., Golovko S.A., Kiven S., Gupta K., Seybold V.S, & Simone D.A. (2022). Inhibition of DAGLβ as a therapeutic target for pain in sickle cell disease. Haematologica, 108(3), 859-869.

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