Standards of anti-arrhythmic drugs (metoprolol, diltiazem, amiodarone, propafenone, 5-hydroxy(OH)-propafenone, verapamil), and stable isotope-labeled compounds (metoprolol-d7, amiodarone-d4, propafenone-d5 and 5OH-propafenone-d5) were supplied by Toronto Research Chemicals (TRC) with purity > 98%. Chemical structures of the analytes were shown in Supplementary Fig. S1 online. HPLC-grade methanol and acetonitrile were purchased from Merck Millipore. Ultra-pure water was prepared with a Milli-Q Plus water system.
Amiodarone
Manufactured by LGC
Sourced in United Kingdom
Amiodarone is a pharmaceutical product used in the treatment of certain types of irregular heartbeat, or arrhythmia. It is a class III antiarrhythmic agent that works by blocking potassium channels in the heart, which helps to stabilize and regulate the heart's electrical activity.
Automatically generated - may contain errors
Lab products found in correlation
Metoprolol, by LGC (1 mentions)
Metoprolol d7, by LGC (1 mentions)
Acetonitrile, by Merck Group (1 mentions)
Hplc grade methanol, by Merck Group (1 mentions)
Astemizole, by Bio-Techne (1 mentions)
Lisinopril, by Fujifilm (1 mentions)
Gentamycin, by Fujifilm (1 mentions)
Mibefradil, by Merck Group (1 mentions)
Atorvastatin, by LGC (1 mentions)
Cisapride, by Abcam (1 mentions)
Ambrisentan, by Selleck Chemicals (1 mentions)
Ketotifen, by Tokyo Chemical Industry (1 mentions)
Terfenadine, by Merck Group (1 mentions)
Terodiline, by Merck Group (1 mentions)
Candesartan, by Selleck Chemicals (1 mentions)
Bepridil, by Bio-Techne (1 mentions)
Bisoprolol, by Selleck Chemicals (1 mentions)
Amlodipine, by Selleck Chemicals (1 mentions)
Linagliptin, by Selleck Chemicals (1 mentions)
Efonidipine, by Merck Group (1 mentions)
2 protocols using amiodarone
1
Quantitative Analysis of Anti-Arrhythmic Drugs
2
Drug Compound Sourcing and Preparation
Check if the same lab product or an alternative is used in the 5 most similar protocols
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Ambrisentan, amlodipine, bisoprolol, candesartan, linagliptin, naftopidil, prasugrel, and sumatriptan were purchased from Selleck Chemicals (Houston, TX, USA). Clonidine, glyburide, lisinopril, nicorandil, and propafenone were obtained from Wako (Tokyo, Japan). Efonidipine, mibefradil, terfenadine, and terodiline were provided by Sigma-Aldrich (St. Louis, MO, USA). Aliskiren and warfarin were from LKT Laboratories (St. Paul, MN, USA); astemizole and bepridil were from Tocris Bioscience (Bristol, UK); amiodarone and atorvastatin were from Toronto Research Chemicals (Toronto, Canada); cisapride was from Abcam (Cambridge, UK); and ketotifen was from Tokyo Chemical Industry (Tokyo, Japan). All compounds were dissolved in a mixture of dimethyl sulfoxide (DMSO) and methanol (7:3), and were stored at -80°C. For cell culture, gentamycin and gelatin (type A, cell culture tested) were obtained from Wako and Sigma-Aldrich, respectively.
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