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Asenapine

Manufactured by Selleck Chemicals

Asenapine is a laboratory instrument designed for chemical analysis and synthesis. It is a versatile tool used in research and development applications to facilitate the measurement, separation, and identification of chemical compounds.

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2 protocols using asenapine

1

High-Throughput Screening of Small Molecule Modulators

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B16.F10 and B16.gp33 (Kindly provided by Dr. H.P. Pircher), MC-38, A549, MDA-MB-231 cell lines were maintained Dulbecco Modified Eagle's Medium (DMEM). Human RPMI-7951 cells were maintained in Eagle’s MEM. MOPC cells were cultured as previously described [70 (link)]. Media was supplemented with 10% FCS (15% for SK-MEL24) and penicillin/streptomycin. Cells were incubated at 37 °C in 5% CO2, and routinely confirmed to be mycoplasma-free (MycoAlert Mycoplasma Detection Kit, Lonza). For screening, the NIH Clinical Collection (NCC) composed of 770 small molecules was used in the screen. 5-Nonyloxytryptamine, Sumatriptan, Forskolin (all from Sigma), Asenapine and the p-CREB 3i inhibitor (SelleckChem) were dissolved in DMSO. Serotonin was dissolved in water (SelleckChem).
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2

Diverse Pharmacological Compounds for Research

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Asenapine (S1283), blonanserin (S2112), droperidol (S4096), ziprasidone (S1444), iloperidone (S1483), amitriptyline (S3183), SB271046 (S2856), ketanserin (S2232), agomelatine (S1243), levosulpiride (S2104), SB742457 (S2894) and chlorprothixene (S1771) were purchased from Selleck. 3-methylade (5142-23-4) was purchased from Energy Chemical. Clozapine (C6305), SB258585 (S1194) and bafiloycinA1 (B1793) were purchased from Sigma. Sertindole (106516-24-9) was purchased from UHN.
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