Eden 260 5

An implant surgery case of the Department of Oral and Maxillofacial Surgery of the Medical Center of the University of Freiburg, Germany was analyzed using the SSM to assess the potential clinical usefulness of the proposed workflow. Plaster casts of the preoperative stage, a corresponding CBCT scan and the virtual planning data had to be available for study inclusion. The implant planning was performed using CoDiagnostix Implant software (Dental Wings Inc., Montreal, Canada). A surgical guide was manufactured by 3D-printing (Eden 260 V, Stratasys, Eden Prairie, USA) to perform surgery.

Different designs of IAMs with directionally asymmetric friction were prepared in SolidWorks and their CAD files were subsequently employed to produce prototype structures utilizing state-of-the-art 3D printing technology. Prototype single-material samples were fabricated using a Stratasys^® Eden 260V and acrylic-based photopolymer materials (FullCure720^®). Composites (multi-material samples) were built with Stratasys^® Connex500 multimaterial 3D printer where the required material stiffness was obtained by blending the stiffest polymer (VeroWhitePlus^®), which simulates conventional thermoplastics, with the softest one - a rubber-like material TangoBlackPlus^®. The polymers based on UV-curable urethanes and acrylates offer the possibility of changing their elastic properties over a broad range by varying the mixing ratios of rigid and flexible phases (see Supplementary Fig. S4 online showing a building tray of the 3D printer).