Na2hpo4

Ti₆Al₄V powder was purchased from AK Medical Co., Ltd, Beijing, China. Icariin and type Ⅰ collagen were purchased from Yuanye Bio-Technology Co., Ltd. Shanghai, China. Na₂HPO₄, CaCl₂, and NaOH were purchased from Macklin Biochemical Technology Co., Ltd., Shanghai, China. Alginate was purchased from Aladdin Biochemical Technology Co., Ltd, Shanghai, China, and its molecular weight ranged from 25 kDa to 50 kDa. Matrigel was purchased from Corning Incorporated, New York, USA. The well plates used for cell experiments were purchased from Corning Incorporated, New York, USA. The low-glucose DMEM medium, RPMI-1640 medium, fetal bovine serum, penicillin, streptomycin, and 0.25 % EDTA were purchased from Gibco, Grand Island, New York, USA.

TeO₂, KH₂PO₄, NaCl, CdCl₂·2.5H₂O, bovine serum albumin (BSA), and l-ascorbic acid (AC)
were all purchased from Shanghai Aladdin Reagent Co., Ltd. KCl, NaOH,
Na₂HPO₄, thiophene (Th), and glutaraldehyde
(GA) were obtained from Shanghai Macklin Biochemical Co., Ltd. Interleukin-6
(IL-6) and IL-6 antibody, MUC1, CEA, and CEA antibody were bought
from Sangon Biotech (Shanghai) Co., Ltd. l(+)-Cysteine (l-Cys), HNO₃, K₄Fe(CN)₆, K₃Fe(CN)₆, acetic acid, and ethanol were bought from
Sinopharm Chemical Reagent Co., Ltd. NaBH₄ was supplied
from Shanghai Energy Chemical Co., Ltd. EIS electrolyte solution consisted
of 5.0 mM [Fe(CN)₆]^3–/4– containing
0.1 M KCl, and the frequency range was 0.1–100 kHz with a signal
amplitude of 5 mV using a Thales electrochemical workstation. All
reagents were of analytical grade and used as obtained without further
purification. The solutions were all prepared with deionized water
(DI water) (18.2 MΩ cm).