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Bioultra grade ammonium formate

Manufactured by Merck Group
Sourced in United States

BioUltra grade ammonium formate is a laboratory-grade chemical compound used as a buffer and ion-pairing agent in analytical procedures. It is characterized by high purity and consistent quality, making it suitable for applications that require precise control of ionic strength and pH.

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3 protocols using bioultra grade ammonium formate

1

Quantification of Cilostazol Analogs in Plasma

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Reference standard of CIL (99.4%), CIL-d11 (99.3%), 3,4-dehydro cilostazol (DCIL, 99.5%) and DCIL-d11 (99.1%) were procured from Clearsynth Labs Pvt. Ltd. (Mumbai, India). HPLC grade methanol and acetonitrile were obtained from Mallinckrodt Baker, S.A.de C.V. (Estado de Mexico, Mexico). BioUltra grade ammonium formate and LC-MS grade formic acid were purchased from Sigma-Aldrich (St. Louis, MO, USA). LiChroSep DVB-HL (30 mg, 1 cc) solid phase extraction cartridges were obtained from Merck Specialties Pvt. Ltd. (Mumbai, India). Deionized water was obtained from Milli-Q water purification system from Millipore (Bangalore, India). Blank human plasma was procured from Supratech Micropath (Ahmedabad, India) and was stored at −70 °C until use.
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2

Quantification of HIV Protease Inhibitors

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Reference standards of atazanavir (99.6%), darunavir (99.2%), and ritonavir (99.3%) and their deuterated internal standards (ISs) atazanavir-d6 (99.1%), darunavir-d9 (99.5%) and ritonavir-d6 (99.0%) were procured from Clearsynth Labs Pvt. Ltd. (Mumbai, India). HPLC grade methanol and acetonitrile were obtained from Mallinckrodt Baker, S.A.de C.V. (Estado de Mexico, Mexico). Bio-ultragrade ammonium formate and LC-MS grade formic acid were purchased from Sigma-Aldrich (St. Louis, MO, USA). Oasis HLB (1 cc, 30 mg) extraction cartridges were from Waters Corporation (Milford, MA, USA). Water used in the study was prepared from Milli-Q water purification system from Millipore (Bangalore, India). Blank human plasma in K3EDTA was obtained from Supratech Micropath (Ahmedabad, India) and was stored at –20°C until use.
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3

Quantification of Lercanidipine in Human Plasma

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Reference standards of lercanidipine hydrochloride (LER, purity 99.66%) and lercanidipine-d3 hydrochloride (IS, purity 99.53%) were obtained from Clearsynth Labs (P) Ltd. (Mumbai, India). HPLC grade methanol and acetonitrile were obtained from Mallinckrodt baker, S.A.de C.V. (Estado de Mexico, Mexico). Bio-ultra grade ammonium formate and LC–MS grade formic acid were procured from Sigma-Aldrich (St. louis, MO, USA). Solid phase extraction (SPE) cartridges Phenomenex Strata™-X (30 mg, 1 mL) were purchased from Phenomenex India (Hyderabad, India). Deionized water used during the entire analysis was prepared using A Milli-Q water purification system from Millipore (Bangalore, India). Blank human plasma was obtained from Supratech Micropath (Ahmedabad, India) and stored at −20 °C until use.
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