Single stage orbitrap exactive ms system

Manufactured by Thermo Fisher Scientific

The Single-Stage Orbitrap (Exactive) MS system is a high-resolution mass spectrometry instrument designed for accurate mass measurements. It utilizes the Orbitrap mass analyzer to provide high-resolution and high-mass accuracy data. The system is capable of analyzing a wide range of sample types and is suitable for various applications, including proteomics, metabolomics, and environmental analysis.

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Lab products found in correlation

Acclaim rslc 120 c18, by Thermo Fisher Scientific (3 mentions) Ultimate 3000 system, by Thermo Fisher Scientific (3 mentions)

Close spelling variants of this product

Exactive Orbitrap MS system Orbitrap Exactive MS Orbitrap Exactive Orbitrap MS

3 protocols using single stage orbitrap exactive ms system

High-Resolution LC-MS Protocol for Metabolomics

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The LC–HRMS system was composed of a Thermo ULTIMATE 3000 system equipped with an analytical column, the Thermo Acclaim RSLC 120 C18 (2.1 mm × 100 mm, 2.2 µm of particle size), coupled to a Thermo Single-Stage Orbitrap (Exactive) MS system, interfaced with a HESI source. The whole equipment setup and the column were from Thermo Fisher Scientific (Milan, Italy). Data were acquired in full scan mode over a mass range of 50 to 750 m/z. The instrument was operated in positive ion mode with a resolving power of 100.000 full width at half maximum (FWHM).
Detailed analytical conditions are reported elsewhere [7 (link)].

Tirri M., Corli G., Arfè R., Marchetti B., Bilel S., Bernardi T., Boccuto F., Odoardi S., Mestria S., Strano-Rossi S, & Marti M. (2023). Behavioral and Pharmacokinetics Studies of N-Methyl-2-Aminoindane (NM2AI) in Mice: An Aminoindane Briefly Used in the Illicit Drug Market. International Journal of Molecular Sciences, 24(3), 1882.

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High-Resolution Liquid Chromatography-Mass Spectrometry

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The LC–HRMS system was composed of a Thermo ULTIMATE 3000 system equipped with an analytical column, a Thermo Acclaim RSLC 120 C18 (2.1 mm × 100 mm, 2.2 μm particle size), coupled to a Thermo single-stage Orbitrap (Exactive) MS system. The entire system was provided by Thermo Fisher Scientific (Milan, Italy).

Rubini S., Rossi S.S., Mestria S., Odoardi S., Chendi S., Poli A., Merialdi G., Andreoli G., Frisoni P., Gaudio R.M., Baldisserotto A., Buso P., Manfredini S., Govoni G., Barbieri S., Centelleghe C., Corazzola G., Mazzariol S, & Locatelli C.A. (2019). A Probable Fatal Case of Oleander (Nerium oleander) Poisoning on a Cattle Farm: A New Method of Detection and Quantification of the Oleandrin Toxin in Rumen. Toxins, 11(8), 442.

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Liquid Chromatography-High Resolution Mass Spectrometry

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The LC–HRMS system was composed of a Thermo ULTIMATE 3000 system equipped with an analytical column Thermo Acclaim RSLC 120 C18 (2.1 × 100 mm, 2.2‐μm particle size), coupled to a Thermo single‐stage Orbitrap (Exactive) MS system, interfaced with a heated electrospray ionization (HESI) source. The whole equipment and the column were from Thermo Fisher Scientific (Milan, Italy).

Odoardi S., Mestria S., Biosa G., Arfè R., Tirri M., Marti M, & Strano Rossi S. (2021). Metabolism study and toxicological determination of mephtetramine in biological samples by liquid chromatography coupled with high‐resolution mass spectrometry. Drug Testing and Analysis, 13(8), 1516-1526.

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