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Tim trio mri

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The Tim Trio MRI is a magnetic resonance imaging (MRI) system manufactured by Siemens. It provides high-quality imaging capabilities for clinical applications. The core function of the Tim Trio MRI is to generate detailed images of the body's internal structures using strong magnetic fields and radio waves.

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Lab products found in correlation

32 channel phased array head coil, by Siemens (3 mentions) Allegra mri, by Siemens (2 mentions) 12 channel head coil, by Siemens (1 mentions) Achieva mri scanner, by Philips (1 mentions) 32 channel head coil, by Siemens (1 mentions)

24 protocols using tim trio mri

1

Multimodal MRI Neuroimaging Protocol

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Structural, DWI, and fMRI data for both timepoints were acquired on a 3T Siemens Trio Tim MRI scanner with a standard Siemens 32-channel phased array head coil. A whole-head, high-resolution T1-weighted multiecho MPRAGE33 (link) anatomical volume was acquired at each timepoint (acquisition parameters: TR = 2350 ms, TE = 1.64 ms, TI = 1400 ms, flip angle = 7°, FOV = 192 × 192, 176 slices, voxel resolution = 1.0 mm3, acceleration = 4). An online prospective motion correction algorithm reduced the effect of motion artifacts during the structural scan, and 10 selective reacquistion images were acquired and included to replace images that were affected by head motion34 (link).
Structural MRI data were processed using a semiautomated processing stream using the default parameters in FreeSurfer v5.2.035 (link),36 (link),37 ,38 (link); http://surfer.nmr.mgh.harvard.edu/), which includes motion and intensity correction, surface coregistration, spatial smoothing, subcortical segmentation, and cortical parcellation based on spherical template registration. The resulting cortical parcellation and subcortical segmentations were individually edited and reviewed for quality control and were used as seeds and targets for DWI tractography (below).
Saygin Z.M., Osher D.E., Norton E.S., Youssoufian D.A., Beach S.D., Feather J., Gaab N., Gabrieli J.D, & Kanwisher N. (2016). Connectivity precedes function in the development of the visual word form area. Nature neuroscience, 19(9), 1250-1255.
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2

Neuroimaging Protocol for Pediatric MRI

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Children were first introduced to the MR scanner setting with a child-friendly mock scanner training, which allowed them to acclimate to the MR environment. Structural neuroimaging was acquired as one aspect of a 40-minute imaging protocol, which included breaks as individually requested, on a 3-T Siemens Trio Tim MRI scanner with a standard Siemens 32-channel phased array head coil. A structural T1-weighted whole-brain anatomical volume was acquired (multiecho MPRAGE; acquisition parameters: TR = 2,350 ms, TE = 1.64 ms, TI = 1,400 ms, flip angle = 7°, FOV = 192 × 192, 176 slices, voxel resolution = 1.0 mm3, acceleration = 4). An online prospective motion correction algorithm was employed to mitigate motion artifacts, in which 10 selective re-acquisition time points were acquired to replace time points impacted by head motion (Tisdall et al., 2012 (link)). To further monitor potential motion during acquisition, a researcher stood near each child in the MRI room to present a physical reminder to stay still throughout the session when necessary. Diffusion-weighted images were acquired with 10 non-diffusion-weighted volumes (b = 0) and 30 diffusion-weighted volumes (acquisition parameters: b = 700 s/mm2, 128 × 128 mm base resolution, isotropic voxel resolution = 2.00 mm3).
Zuk J., Dunstan J., Norton E., Yu X., Ozernov-Palchik O., Wang Y., Hogan T.P., Gabrieli J.D, & Gaab N. (2020). Multifactorial pathways facilitate resilience among kindergarteners at risk for dyslexia: A longitudinal behavioral and neuroimaging study. Developmental science, 24(1), e12983.
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3

Multimodal MRI Neuroimaging Protocol

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DTI and high-resolution T1-weighted MRI data were acquired using a 3.0 Tesla Siemens Trio Tim MRI scanner with a 12-channel head coil at the Shanghai Key Laboratory of Magnetic Resonance (East China Normal University, Shanghai, China). Custom-fit foam pads were used to minimize head movement of the subjects. The parameters of the pulse sequence were as follows: 1) high-resolution T1-weighted 3-dimensional magnetization-prepared rapid-acquisition gradient-echo pulse sequence, repetition time = 2530 ms, echo time = 2.34 ms, inversion time = 1100 ms, flip angle = 7°, number of slices = 192, sagittal orientation, field of view = 256 × 256 mm2, matrix size = 256 × 256, and slice thickness = 1 mm. 2) The DTI acquisition utilized a single-shot spin-echo echo planar imaging sequence in the contiguous axial plane, repetition time = 8900 ms, echo time = 86 ms, b-value = 0 and 1000 s/mm2, slice thickness = 2 mm, and 70 slices, matrix size = 128 × 128, field of view = 256 × 256 mm2, diff direction = 64, and the resolution = 2 × 2 × 2 mm3.
Zhang J., Wu Y.L., Su J., Yao Q., Wang M., Li G.F., Zhao R., Shi Y.H., Zhao Y., Zhang Q., Lu H., Xu S., Qin Z., Cui G.H., Li J., Liu J.R, & Du X. (2017). Assessment of gray and white matter structural alterations in migraineurs without aura. The Journal of Headache and Pain, 18(1), 74.
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4

Multimodal Neuroimaging of Healthy Brains

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Anatomical T1-weighted and functional T2*-weight MR images were conducted on a 3-Tesla Siemens Trio Tim MRI scanner, using a 12-channel phased-array head coil at the Magnetic Resonance Imaging Lab, South China Normal University. Functional images were acquired using a T2*-weighted gradient echo, echo-planar imaging sequence (32 axial slices covering the whole brain, TR = 2000 ms, TE = 30 ms, flip angle = 90°, FOV = 192 mm, inter-slice gap = 1 mm, slice thickness = 3 mm, matrix size = 64 × 64). After the functional scanning, a high-resolution T1-weighted anatomical scan was acquired by using a MP-RAGE sequence (TR = 1900 ms, TE = 2.52 ms, flip angle = 9°, voxel-size = 1 mm × 1 mm × 1 mm).
Zhang W., He X., Lai S., Wan J., Lai S., Zhao X, & Li D. (2017). Neural substrates of embodied natural beauty and social endowed beauty: An fMRI study. Scientific Reports, 7, 7125.
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5

Multimodal MRI Neuroimaging Protocol

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Structural, DWI, and fMRI data for both timepoints were acquired on a 3T Siemens Trio Tim MRI scanner with a standard Siemens 32-channel phased array head coil. A whole-head, high-resolution T1-weighted multiecho MPRAGE33 (link) anatomical volume was acquired at each timepoint (acquisition parameters: TR = 2350 ms, TE = 1.64 ms, TI = 1400 ms, flip angle = 7°, FOV = 192 × 192, 176 slices, voxel resolution = 1.0 mm3, acceleration = 4). An online prospective motion correction algorithm reduced the effect of motion artifacts during the structural scan, and 10 selective reacquistion images were acquired and included to replace images that were affected by head motion34 (link).
Structural MRI data were processed using a semiautomated processing stream using the default parameters in FreeSurfer v5.2.035 (link),36 (link),37 ,38 (link); http://surfer.nmr.mgh.harvard.edu/), which includes motion and intensity correction, surface coregistration, spatial smoothing, subcortical segmentation, and cortical parcellation based on spherical template registration. The resulting cortical parcellation and subcortical segmentations were individually edited and reviewed for quality control and were used as seeds and targets for DWI tractography (below).
Saygin Z.M., Osher D.E., Norton E.S., Youssoufian D.A., Beach S.D., Feather J., Gaab N., Gabrieli J.D, & Kanwisher N. (2016). Connectivity precedes function in the development of the visual word form area. Nature neuroscience, 19(9), 1250-1255.
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6

Multisite Neuroimaging Protocol for Functional Connectivity

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All the Taiwan, COBRE, and Xiangya imaging data were acquired using a 3-T Siemens Trio Tim MRI scanner with an eight or a twelve channel phased array head coil, whereas that from Huaxi data were acquired using a 3-T General Electric MRI scanner. The Nottingham data set was acquired using a 3-T Philips Achieva MRI scanner. During data acquisition, the subjects were instructed to keep their eyes closed but not fall asleep (Huaxi, Taiwan, and Xiangya sites) or to remain with their eyes open staring at a fixation cross (COBRE and Nottingham sites). Image preprocessing steps included slice timing, within-subject realignment, spatial normalization to the stereotactic space of the Montreal Neurological Institute with voxel size of 3×3×3 mm3, linear detrending, band-pass filtering (0·01~0·08 Hz), and scrubbing. In all cases the data were smoothed spatially (FWHM 8 mm) and nuisance signal were regressed (including six motion parameters, the global, white matter, and cerebrospinal fluid signals). Any data affected by head motion (maximal motion between volumes in each direction, and rotation about each axis) of >3 mm or rotation of >3° was excluded. The Supplementary Information provides additional details of the imaging acquisition and data preprocessing.
Cheng W., Palaniyappan L., Li M., Kendrick K.M., Zhang J., Luo Q., Liu Z., Yu R., Deng W., Wang Q., Ma X., Guo W., Francis S., Liddle P., Mayer A.R., Schumann G., Li T, & Feng J. (2015). Voxel-based, brain-wide association study of aberrant functional connectivity in schizophrenia implicates thalamocortical circuitry. NPJ Schizophrenia, 1, 15016-.
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7

Resting-state fMRI Protocol in 3T Siemens Trio

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All participants were scanned in a 3T Siemens Trio Tim MRI scanner (Siemens, Erlangen, Germany) with an eight-channel phased array head coil. The experiments were conducted in the Key Laboratory of Cognition and Personality of Ministry of Education, Southwest University, China. The functional images were acquired using 2D gradient echo-planar imaging (EPI) sequences, with the following imaging parameters: thickness = 3 mm (with 1 mm gap), repetition time (TR) = 2,000 ms, echo time (TE) = 30 ms, field of view (FOV) = 22 × 22 cm, flip angle = 90°, and matrix = 64 × 64. A total of 205 volumes (32 slices per volume) were acquired during 410 seconds. To ensure steady-state longitudinal magnetization, the first five volumes were discarded. During data acquisition, participants were instructed to relax with their eyes closed, without falling asleep. Anatomical T1-weighted images were acquired using a three-dimensional- (3D-) spoiled gradient recalled sequence, generating 176 axial slices (thickness = 1 mm (no gap), TR = 8.5 ms, TE = 3.4 ms, FOV = 24 × 24 cm, flip angle = 12°, and matrix = 512 × 512).
Luo C., Tu S., Peng Y., Gao S., Li J., Dong L., Li G., Lai Y., Li H, & Yao D. (2014). Long-Term Effects of Musical Training and Functional Plasticity in Salience System. Neural Plasticity, 2014, 180138.
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8

Voxel-Based Morphometry of Brain Structures

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High-resolution T1-weighted images were acquired on a Siemens 3-Tesla TimTrio MRI with an 8-channel birdcage type Invivo coil with the following parameters: 3D MPRAGE, TR=1540 ms, TE=2.3 ms, voxel spacing 1.0×1.0×1.0 mm, image resolution 256×256 mm2, and 176 slices with no gap.
A VBM analysis was carried out using the FMRIB Software Library (FSL) tools [16 (link)]. First, brain-extracted structural images were segmented into gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF). Next, GM images were registered to a standard space and averaged to create the study-specific template. Individual GM images then were non-linearly registered to the study-specific template (spatial normalization). The resulting GM images were modulated by multiplying with Jacobian determinants to correct for volume change induced by the nonlinear spatial normalization. Finally, the images were smoothed with an isotropic Gaussian kernel of 9 mm. For the statistical analysis, permutation-based non-parametric testing (5000 permutations) was used with adjustments for depression [17 (link)] and total intracranial volume. Based on a priori hypotheses, group differences were considered significant at uncorrected p< 0.005 for limbic and paralimbic cortex, including PC and OFC, and at FWE (family-wise) corrected p< 0.05 for other brain regions.
Lee E.Y., Eslinger P.J., Du G., Kong L., Lewis M.M, & Huang X. (2014). Olfactory-related cortical atrophy is associated with olfactory dysfunction in Parkinson’s disease. Movement disorders : official journal of the Movement Disorder Society, 29(9), 1205-1208.
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9

Resting-state fMRI Acquisition Protocol

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MRI scanning was performed on a 3.0 T Siemens Tim Trio MRI (Erlangen, Germany). The resting-state fMRI images were acquired using a gradient-echo-planer imaging (EPI) sequence, the scan parameters were as follows: TR = 2000 ms, TE = 35 ms, flip angle FA = 68°, slice thickness = 3 mm (no slice gap), matrix size = 64 × 64, FOV = 208 × 208 mm2, time point = 220, and acquisition time = 7.26 min, resulting in a voxel size of 3.3 × 3.3 × 3.0 mm3 (link). Subjects were instructed to close their eyes, remain still, and relax, without falling asleep during scanning.
Wu X., Liu W., Wang W., Gao H., Hao N., Yue Q., Gong Q, & Zhou D. (2019). Altered intrinsic brain activity associated with outcome in frontal lobe epilepsy. Scientific Reports, 9, 8989.
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10

Standardized Brain MRI Imaging for Longitudinal Treatment Monitoring

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Standardised serial brain MRIs were acquired pre-treatment (all patients) and at month 12 (n = 27) and month 24 (n = 29) on-treatment on a 3 T Siemens TIM Trio MRI scanner (Siemens Healthcare, Erlangen, Germany). Serial scans from each individual were performed consistently using the same receiver coil. Axial 2D, T2-weighted images were acquired using a turbo spin-echo (TSE) sequence with TR = 4500 ms, TE = 83 ms, turbo factor = 11, in-plane voxel dimensions of 1 × 1 mm2 and slice thickness = 3 mm; Axial 2D, proton density-weighted images were acquired using a TSE sequence with TR = 2200 ms, TE = 10 ms, turbo factor = 4, in-plane voxel dimensions of 1 × 1 mm2 and slice thickness = 3 mm; Axially-acquired 3D, T1-weighted images were acquired using a 3D, fast, low-angle shot (FLASH) sequence with TR = 28 ms, TE = 6.15 ms, flip angle = 27 degrees, in-plane voxel dimensions of 1 × 1 mm2 and slice partition thickness = 3 mm; Sagittal 3D fluid-attenuated inversion recovery (FLAIR) images were acquired using an inversion-prepared variable flip angle TSE sequence with TI = 2200 ms, TR = 6 s, TE = 355 ms, turbo factor = 141, isotropic 1 mm3 voxels and GRAPPA acceleration factor R = 2 in the first phase encode direction.
Ghadiri M., Rezk A., Li R., Evans A., Giacomini P.S., Barnett M.H., Antel J, & Bar-Or A. (2020). Pre-treatment T-cell subsets associate with fingolimod treatment responsiveness in multiple sclerosis. Scientific Reports, 10, 356.
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