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Kolliphor p188 kp188

Manufactured by Merck Group
Sourced in Japan, United States

Kolliphor® P188 (KP188) is a non-ionic surfactant produced by Merck. It is a polyethylene glycol (PEG) derivative that functions as a wetting agent, emulsifier, and solubilizer in various pharmaceutical and industrial applications.

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2 protocols using kolliphor p188 kp188

1

Preparation of Saline and Buffer Solutions

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Physiological saline (saline) was supplied by Otsuka Pharmaceutical Factory, Inc. (Tokushima, Japan). Pure water was prepared using Elix® UV3 (Sigma-Aldrich Japan Ltd., Tokyo, Japan). Phosphate buffered saline (PBS) was purchased from Life Technologies Japan (Tokyo, Japan). Kolliphor® P188 (KP188) and Polysorbate 20 (Tween 20) were purchased from Sigma-Aldrich Japan Ltd. Bovine serum albumin (BSA) was purchased from Carbochem Co., Ltd. (Jiangsu, China). Solutions of 0.5% KP188 and 0.1% Tween 20 in physiological saline (154 mM NaCl in H2O) and 0.5% BSA in PBS were prepared and frozen until use.
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2

Lipid-based Drug Delivery Formulations

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Wheat germ agglutinin (WGA) from Triticum Vulgare was purchased from Vector laboratories (Burlingame, CA, USA) and HOECHST 33342 from Invitrogen (Paisley, UK). Human serum albumin (HSA), cottonseed oil, Kolliphor® P188 (KP188) and the cell culture medium RPMI-1640 were obtained from Sigma-Aldrich (St. Louis, MO, USA). BodiPy® 493/503 (BodiPy®) was bought from Invitrogen (Eugene, Oregon, USA). n-Dodecane, olive oil, almond oil, rapeseed oil and linseed oil were purchased from Carl Roth GmbH & Co. KG (Karlsruhe, Germany). All other chemicals used were obtained from Carl Roth GmbH & Co. KG (Karlsruhe, Germany) or Sigma Aldrich (Seelze, Germany).
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