Rds eclipse rd hp medical cyclotron

Manufactured by Siemens

Sourced in Japan

The RDS eclipse RD/HP medical cyclotron is a laboratory equipment used for the production of medical radioisotopes. It is designed to accelerate charged particles for nuclear reactions, which are then used in the manufacture of radiopharmaceuticals for medical imaging and treatment purposes.

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Lab products found in correlation

Tracerlab mxfdg, by GE Healthcare (1 mentions) 18o water, by Cambridge Isotopes (1 mentions)

2 protocols using rds eclipse rd hp medical cyclotron

Radiolabeling of [18F]NaF via Cyclotron

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No-carrier-added [¹⁸F]fluoride was produced via the ¹⁸O(p,n)¹⁸F reaction from > 98% enriched [¹⁸O]water (Taiyo Nippon Sanso Corporation, Tokyo, Japan) on an RDS eclipse RD/HP medical cyclotron (Siemens, Knoxville, TN, USA). [¹⁸F]NaF was prepared by eluting [¹⁸F]fluoride trapped on an anion exchange column (QMA Plus Light; Waters Corporation, Milford, MA, USA) with saline after washing the anion exchange column with water.

Ogawa K., Ishizaki A., Takai K., Kitamura Y., Makino A., Kozaka T., Kiyono Y., Shiba K, & Odani A. (2017). Evaluation of Ga-DOTA-(D-Asp)n as bone imaging agents: D-aspartic acid peptides as carriers to bone. Scientific Reports, 7, 13971.

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Synthesis of 18F-FLT Radiotracer

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¹⁸F-FLT was synthesized in a TRACERlab MXFDG (GE Healthcare) using an ABX-FLT kit (ABX) [14 (link)]. No-carrier-added ¹⁸F-fluoride was produced via the ¹⁸O(p,n)¹⁸F reaction from > 98% enriched ¹⁸O-water (Cambridge Isotope Laboratories) on an RDS eclipse RD/HP medical cyclotron (Siemens/CTI). The radiochemical purity of the final product was > 99%, and the yield was 12.3 ± 4.6% (end of synthesis, n = 17).

Tsujikawa T., Tasaki T., Hosono N., Mori T., Makino A., Kiyono Y., Zanotti-Fregonara P., Yamauchi T, & Okazawa H. (2019). 18F-FLT PET/MRI for bone marrow failure syndrome-initial experience. EJNMMI Research, 9, 16.

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