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Cetrorelix

Manufactured by Cayman Chemical
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Sourced in United States

Cetrorelix is a laboratory product manufactured by Cayman Chemical. It is a synthetic gonadotropin-releasing hormone antagonist.

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Lab products found in correlation

Flutamide, by Merck Group (1 mentions) Ici 182 780, by Bio-Techne (1 mentions) Bromodeoxyuridine (brdu), by Merck Group (1 mentions) Sb204741, by Bio-Techne (1 mentions) Fatty acid free bsa, by Equitech-Bio (1 mentions) Amicon ultra 0.5 centrifugal filter unit, by Merck Group (1 mentions) Harmine, by Merck Group (1 mentions)

2 protocols using cetrorelix

1

Biochemical Modulators of Cell Signaling

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The GNRHR antagonist Cetrorelix was from Cayman Chemicals (catalog 23910-10), the selective HTR2B receptor antagonist SB204741 and the estrogen receptor antagonist ICI 182,780 were from Tocris (catalogs 1372/10 and 1047/1, respectively). Recombinant rat GH protein (rGH) was from Abcam (catalog ab68388). BrdU, the androgen receptor antagonist flutamide, and the DYRK1A inhibitor harmine were from Sigma-Aldrich (catalogs B5002, F9397, and 286044, respectively). The insulin receptor antagonist S961 was from Phoenix Pharmaceuticals (catalog 05186). The Amicon Ultra-0.5 Centrifugal Filter Units were from MilliporeSigma (catalog UFC500324). Fatty acid–free BSA was obtained from Equitech-Bio.
Castell A.L., Goubault C., Ethier M., Fergusson G., Tremblay C., Baltz M., Dal Soglio D., Ghislain J, & Poitout V. (2022). β Cell mass expansion during puberty involves serotonin signaling and determines glucose homeostasis in adulthood. JCI Insight, 7(21), e160854.
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2

Preparation of GnRH Analogue Solutions

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All chemicals were purchased from Sigma-Aldrich (St. Louis, MO, United States) unless otherwise described. GnRH was purchased from Anygen (Gwangju, Korea). Cetrorelix and goserelin were purchased from Cayman Chemicals (Ann Arbor, MI, United States). Stock solutions were prepared using water or dimethyl sulfoxide and diluted with test solutions before use.
Zheng H., Kim M., Kim C., Kim Y., Cho P.S., Lim J.Y., Lee H., Yun H.I., Choi J, & Hwang S.W. (2024). GnRH peripherally modulates nociceptor functions, exacerbating mechanical pain. Frontiers in Molecular Neuroscience, 17, 1160435.
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