Polyoxyethylene sorbitan monooleate tween 80

Manufactured by Tokyo Chemical Industry

Sourced in Japan

Polyoxyethylene sorbitan monooleate, commonly known as Tween 80, is a non-ionic surfactant that is used as a dispersing agent, emulsifier, and solubilizer in various applications. It is a clear, viscous liquid with a mild odor and is soluble in water and other polar solvents.

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Lab products found in correlation

1 2 dimyristoyl sn glycero 3 phosphocholine, by NOF corporation (3 mentions) 1 2 dipalmitoyl sn glycero 3 phosphocholine, by NOF corporation (3 mentions) 1 2 distearoyl sn glycero 3 phosphocholine, by NOF corporation (3 mentions) Acetic acid, by Fujifilm (1 mentions) Benzalkonium chloride, by Fujifilm (1 mentions) Methanol, by Fujifilm (1 mentions) Acetonitrile, by Fujifilm (1 mentions) Ethanol 99.5, by Fujifilm (1 mentions) 1 2 dio leoyl sn glycero 3 phosphocholine, by NOF corporation (1 mentions)

3 protocols using polyoxyethylene sorbitan monooleate tween 80

Lipid Characterization and Phospholipid Selection

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LA was purchased from Shin Nippon Yakugyo Co Ltd. (Tokyo, Japan). C17MGE was provided by Farnex Inc. (Yokohama, Japan). Table I shows the chemical structures of LA and C17MGE. Among phospholipids, 1, 2-distearoyl-sn-glycero-3-phosphocholine (DSPC) was selected as a saturated example and 1, 2-dioleoyl-sn-glycero-3-phosphoglycerol, sodium salt (DOPG), 1, 2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE), and phosphocholine (DOPC) were selected as unsaturated phospholipids. These phospholipids were purchased from NOF Corporation (Tokyo, Japan). Table II shows the chemical structure of these phospholipids. This table also shows the abbreviations used for the phospholipids. Polyoxyethylene sorbitan monooleate (Tween 80) was purchased from Tokyo Chemical Industries, Ltd. (Tokyo, Japan). All other regents were used without further purification.Table I.

Structures of LA and MGE

Table II.

Structure of Phospholipids

Okada A., Todo H., Itakura S., Hijikuro I, & Sugibayashi K. (2021). A Lipid-Based Depot Formulation with a Novel Non-lamellar Liquid Crystal Forming Lipid. Pharmaceutical Research, 38(3), 503-513.

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Quantitative Analysis of hGhrelin

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hGhrelin was obtained from Asubio Pharma (Kobe, Japan). Tamibarotene (Am80) was provided by Ituu Laboratory (Tokyo, Japan). Nicotinamide (VB₃) was purchased from Sigma-Aldrich Japan (Tokyo, Japan). Cyanocobalamin (VB₁₂) and polyoxyethylene sorbitan monooleate (Tween 80) were purchased from Tokyo Chemical Industry (Tokyo, Japan). Ammonium acetate (reagent grade) was purchased from Nacalai Tesque (Kyoto, Japan). L-phenylalanine (Phe, special grade), ethanol (99.5%) (reagent grade), acetonitrile (HPLC (high-performance liquid chromatography) grade), benzalkonium chloride, acetic acid (special grade), dimethyl sulfoxide (DMSO, reagent grade), trifluoro acetic acid (TFA, special grade), and methanol (HPLC grade) were all purchased from Fujifilm Wako Pure Chemical Industries (Osaka, Japan).
The packaging materials used in this study were obtained from the following commercial vendors: 2-mL VIST glass vials from Daiwa Special Glass (Osaka, Japan) and rubber stoppers (F5-43) from Sumitomo Rubber Industries (Kobe, Japan).

Miyamoto K., Taga H., Akita T, & Yamashita C. (2020). Simple Method to Measure the Aerodynamic Size Distribution of Porous Particles Generated on Lyophilizate for Dry Powder Inhalation. Pharmaceutics, 12(10), 976.

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Lipid Bilayer Membrane Preparation

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FD-4 was obtained from Sigma-Aldrich (St. Louis, MO, USA). 1,2-Dimyristoylsn-glycero-3-phosphocholine (DMPC), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), and 1,2-dioleoyl-snglycero-3-phosphocholine (DOPC) were purchased from NOF Corporation (Tokyo, Japan). MGE was kindly provided by Farnex Inc. (Yokohama, Japan). Polyoxyethylene sorbitan monooleate (Tween 80) was obtained from Tokyo Chemical Industry (Tokyo, Japan). All other regents were used without further purification.

Okada A., Todo H., Hijikuro I., Itakura S, & Sugibayashi K. (2020). Controlled release of a model hydrophilic high molecular weight compound from injectable non-lamellar liquid crystal formulations containing different types of phospholipids. International journal of pharmaceutics, 577.

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